恶性青光眼诊治进展  

The progress of diagnosis and treatment of malignant glaucoma

作　　者：郑选力 林海双 李家倩 雷长荣 万芮 叶雯青 梁远波 Zheng Xuanli;Lin Haishuang;Li Jiaqian;Lei Changrong;Wan Rui;Ye Wenqing;Liang Yuanbo(National Clinical Research Center for Ocular Diseases,Eye Hospital,Wenzhou Medical University,Wenzhou Zhejiang 325027,China)

机构地区：[1]温州医科大学附属眼视光医院,国家眼耳鼻喉疾病(眼部疾病)临床医学研究中心,浙江温州325027

出　　处：《国际眼科纵览》2024年第5期321-326,共6页International Review of Ophthalmology

基　　金：浙江省万人计划科技创新领军人才(2021R52012);浙江省"尖兵""领雁"研发攻关计划(2022C03112)。

摘　　要：恶性青光眼是最严重的青光眼手术并发症之一,主要包括典型恶性青光眼、白内障术后恶性青光眼和其他原因继发恶性青光眼三种类型。浅前房、短眼轴、厚晶状体等解剖因素及年轻、女性、诊断为闭角型青光眼、外滤过手术史、术前高眼压是恶性青光眼发生的危险因素。跨晶状体压力差假说为重新认识和理解恶性青光眼的发病机制提供新角度,并可为恶性青光眼防治带来新思路。解除睫状体阻滞、恢复晶状体前后房水流动是恶性青光眼治疗中的关键。Malignant glaucoma is one of the most severe complications of glaucoma surgery.It mainly includes three types:typical malignant glaucoma,malignant glaucoma after cataract surgery,and other secondary malignant glaucoma.Anatomical factors such as a shallow anterior chamber,short axial length,and thick lens,as well as being young,female,diagnosed with angle-closure glaucoma,having a history of external filtration surgery,and preoperative high intraocular pressure,are considered risk factors for the occurrence of malignant glaucoma.The hypothesis of trans-lens pressure differential provides a new perspective for rethinking and understanding the pathogenesis of malignant glaucoma,and may offer new strategies for its prevention and treatment.Relieving ciliary block and restoring the flow of aqueous humor between the anterior and posterior chambers of the eye are key in the treatment of malignant glaucoma.

关 键 词：恶性青光眼 跨晶状体压力差 睫状体阻滞 

分 类 号：R775[医药卫生—眼科]