药物及个人护理用品的生态毒理  

Research Progress of Ecotoxicology of PPCP Pollutants

作　　者：高川子 廖浩麟 王毅博 郑一 郑春苗 裘文慧 Chuanzi Gao;Haolin Liao;Yibo Wang;Yi Zheng;Chunmiao Zheng;Wenhui Qiu(Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control,School of Environmental Science and Engineering,Southern University of Science and Technology,Shenzhen 518055,China)

机构地区：[1]南方科技大学环境科学与工程学院广东省土壤与地下水污染防控及修复重点实验室,深圳518055

出　　处：《化学进展》2024年第9期1363-1379,共17页Progress in Chemistry

基　　金：国家自然科学基金项目(No.42322707,42077223,42277266);广东省基础与应用基础研究基金(2023A1515140118)资助。

摘　　要：药物及个人护理用品(PPCPs)是近年来受高度关注的一大类新兴污染物。PPCPs的大量生产和快速消费需求,使其广泛进入并普遍存在各大环境介质中,由于迁移转化和生物蓄积作用,PPCPs进入生态环境,对生物体和人体造成不同程度的负面影响,给生态环境和人体健康带来严重威胁。本文总结了目前PPCPs在环境中的暴露来源、途径及特征,归纳总结了PPCPs在环境中的降解方法及途径,综述了PPCPs的主要生物毒性效应,概述了PPCPs在人体的内暴露情况及其对人体健康的影响,最后对PPCPs生态毒理方向的研究方向进行了展望。Pharmaceuticals and personal care products(PPCPs)are a large category of emerging pollutants that have been highly concern in recent years.The huge production and rapid consumption demand of PPCPs make them widely enter and highly exist in various environmental mediums.Due to migration,transformation and bioaccumulation,PPCPs enter the ecological environment,causing different degrees of negative impact on organisms and human bodies,thus bringing serious threats to the ecological environment and human health.In this review,we summarize the exposure sources,pathways and characteristics of current PPCPs in the environment,conclude the degradation method and pathway of PPCPs in the environment,review the main biotoxicity of PPCPs,overview the exposure concentrations and the health influences on the human body,and finally have some outlooks on the research field of ecotoxicity of PPCPs.

关 键 词：药物及个人护理用品 降解率 生物毒性 生态毒理 人体健康风险 

分 类 号：X171.5[环境科学与工程—环境科学] X131