右侧阴囊丘疹性棘层松解角化不良1例  

A case of papular acantholytic dyskeratosis of the right scrotum

作　　者：魏孔熙 张茹[1] 杜进苹 聂芳 眭岩 刘永琦 WEI Kongxi;ZHANG Ru;DU Jinping;NIE Fang;SUI Yan;LIU Yongqi(Third Affiliated Hospital of Gansu University of Traditional Chinese Medicine,First People′s Hospital of Baiyin City,Baiyin 730900,China;Provincial Key Laboratory for Molecular Medicine of Major Disaseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and Universities,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学第三附属医院,白银市第一人民医院,甘肃白银730900 [2]甘肃中医药大学甘肃省高校重大疾病分子医学与中医药防治研究省级重点实验室,甘肃兰州730000

出　　处：《皮肤性病诊疗学杂志》2024年第10期701-704,共4页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：甘肃省“双一流”科研重点项目(GSSYLXM-05);甘肃中医药大学第三附属医院培育项目(2021PY-03)。

摘　　要：报告右侧阴囊丘疹性棘层松解角化不良1例。患者男,58岁。因右侧阴囊丘疹伴瘙痒5年余就诊。皮肤科检查:右侧腹股沟及大腿根部大片密集或散在的粟粒至绿豆大小的丘疹,部分呈斑块状,表面轻微糜烂、浸渍、发白。皮损组织病理检查:角化过度,角化不全,表皮不规则增生,棘层松解,形成表皮内疱,可见较多角化不良细胞,真皮浅层淋巴细胞及浆细胞浸润。诊断:丘疹性棘层松解角化不良。予CO_(2)点阵激光治疗。2年后随访,患者皮疹反复发作,时轻时重。To report a case of popular acantholytic dyskeratosis of the right scrotum.A 58-year-old man complained of pruritic papules on the right scrotum for over 5 years.Dermatologic examination revealed unevenly distributed,millet to green bean sized papules with erosion and maceration,on the right groin.Histopathological changes included hyperkeratosis,parakeratosis,irregular epidermal hyperplasia,acantholysis,intraepidermal vesicles,with a large number of dyskeratotic cells in addition to infiltration of lymphocytes and plasma cells in the dermis.Patient was diagnosed with papular acantholytic dyskeratosis and treated with fractional CO_(2)laser,and the rashes repeatedly relapsed when followed up 2 years later.

关 键 词：棘层松解 角化不良 丘疹 阴囊 CO_(2)点阵激光 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]