不同供氧方式高压氧治疗对手术治疗后卒中患者经皮氧分压影响的研究  

Effects of Different Oxygen Supply Methods during Hyperbaric Oxygen Therapy on the Transcutaneous Oximetry of Post-Surgery Stroke Patients

作　　者：任梓齐 王勤芳 刘亚玲[1] 王丛 于秋红[1] REN Ziqi;WANG Qinfang;LIU Yaling;WANG Cong;YU Qiuhong(Department of Hyperbaric Oxygen,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Hyperbaric Oxygen,Shandong Second Medical University Affiliated Qingdao Eighth People’s Hospital,Qingdao 266100,China)

机构地区：[1]首都医科大学附属北京天坛医院高压氧科,北京100070 [2]青岛市第八人民医院高压氧科

出　　处：《中国卒中杂志》2024年第10期1148-1154,共7页Chinese Journal of Stroke

基　　金：国家重点研发计划(2023YFB4706101);科技创新2030-“脑科学与类脑研究”重大项目(2021ZD0204200);首都医科大学-盈康一生科创菁英培育计划(2024KCJY0208)。

摘　　要：目的评估不同供氧方式的高压氧治疗下,发病30 d内卒中术后患者经皮氧分压(transcutaneous oximetry,TcPO_(2))的变化。方法回顾性纳入2023年1月1日—2024年6月20日在高压氧科接受治疗的发病30 d内卒中术后患者,根据气道情况分为正常气道面罩加储气囊供氧(面罩组)和人工气道头罩供氧(头罩组)。高压氧治疗期间实时监测TcPO_(2),比较两种供氧方式下TcPO_(2)变化。结果本研究共入选26例患者,面罩组和头罩组各13例。面罩组升压开始时TcPO_(2)为(55.92±9.58)mmHg(1 mmHg=0.133 kPa),稳压吸氧阶段TcP O_(2)平均值和最大值分别为(679.30±186.80)mmHg和(881.40±208.20)mmHg,减压结束TcPO_(2)为(83.71±21.54)mmHg。头罩组升压开始时TcPO_(2)为(62.92±14.84)mmHg,稳压吸氧阶段TcPO_(2)平均值和最大值分别为(369.50±163.00)mmHg和(487.90±212.10)mmHg,减压结束TcPO_(2)为(84.25±19.95)mmHg。面罩组稳压吸氧阶段TcPO_(2)的平均值和最大值高于头罩组相应指标,差异有统计学意义(P<0.01)。面罩组和头罩组稳压吸氧10 min TcPO_(2)开始升高,面罩组吸氧30 min TcPO_(2)达到饱和,头罩组随吸氧时间延长TcPO_(2)动态上升直至吸氧结束。结论高压氧治疗期间,面罩供氧和头罩供氧均能提升卒中术后患者的TcPO_(2)水平,面罩吸氧效果应该优于头罩。Objective To evaluate the changes in transcutaneous oximetry(TcPO_(2))within 30 days of stroke onset in post-surgery patients under hyperbaric oxygen therapy with different oxygen supply methods.Methods Post-surgery stroke patients who received treatment in the hyperbaric oxygen department within 30 days of onset from January 1,2023 to June 20,2024 were included in this retrospective analysis.According to the airway condition,normal airway patients were supplied with a mask and reservoir bag(the mask group)and artificial airway patients with ventilator weaning were supplied with a head hood(the head hood group).The TcPO_(2)was monitored in real time during hyperbaric oxygen therapy and compared the changes of TcPO_(2)between the two oxygen supply methods.Results A total of 26 patients were included in this study,including 13 patients in the mask group and 13 patients in the head hood group.In the mask group,TcPO_(2)was(55.92±9.58)mmHg(1 mmHg=0.133 kPa)before compression,and the mean and maximum TcPO_(2)during oxygen inhalation stage were(679.30±186.80)mmHg and(881.40±208.20)mmHg,respectively.After decompression,TcPO_(2)was(83.71±21.54)mmHg.In the head hood group,TcPO_(2)was(62.92±14.84)mmHg before compression,the mean and maximum TcPO_(2)during oxygen inhalation stage were(369.50±163.00)mmHg and(487.90±212.10)mmHg,respectively.After decompression,TcPO_(2)was(84.25±19.95)mmHg.The mean and maximum of TcPO_(2)during oxygen inhalation stage in the mask group were higher than those in the head hood group,and the differences were statistically significant(P<0.01).The TcPO_(2)of the mask group and the head hood group began to increase after oxygen inhalation for 10 minutes.In the mask group,TcPO_(2)reached the saturation at 30 minutes,while in the hood group,TcPO_(2)increased dynamically with the extension of oxygen inhalation time until the end of oxygen inhalation.Conclusions During hyperbaric oxygen therapy,both mask oxygen supply and head hood oxygen supply increased the TcPO_(2)level of post-surgery stroke

关 键 词：高压氧 经皮氧分压 卒中 面罩吸氧 头罩吸氧 

分 类 号：R74[医药卫生—神经病学与精神病学]