预测老年肿瘤患者化疗毒性的工具评价  

Evaluation of tools for predicting chemotherapeutic toxicity in elderly cancer patients

作　　者：付玉翠 姜秋颖[1] FU Yucui;JIANG Qiuying(Department of Medical Oncology,the Second Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院肿瘤内科,黑龙江哈尔滨150086

出　　处：《现代肿瘤医学》2024年第22期4401-4404,共4页Journal of Modern Oncology

摘　　要：随着人口老龄化日益加剧,老年肿瘤患者逐渐增多。老年肿瘤患者身体机能下降,易合并各类疾病,这使他们在化疗时不良反应明显,化疗风险增加,化学治疗亦受到一定限制。然而,目前的临床试验中老年患者代表性不足,照搬指南治疗可能对老年患者不利,但如果仔细选择和监测,有的老年患者可规避严重的化疗毒性,有的也可在化疗中受益。该文对预测老年肿瘤患者化疗毒性的工具进行综述,以帮助临床医生选择最佳的预测工具。With the aging of the population,the number of elderly patients with cancer is increasing.The physical function of elderly tumor patients is decreased,and they are easy to combine with various diseases,which makes them have obvious adverse reactions and increased risk of chemotherapy,and chemotherapy is limited.However,the current clinical trials are underrepresented in elderly patients,and copying the guidelines may be detrimental to elderly patients.However,if carefully selected and monitored,some elderly patients can avoid the serious toxicity of chemotherapy,and some can also benefit from chemotherapy.This article reviews the tools used to predict the toxicity of chemotherapy in elderly patients with cancer,in order to help clinicians choose the best tool.

关 键 词：老年患者 化疗毒性 预测工具 

分 类 号：R730.5[医药卫生—肿瘤]