Emergence of Multidrug-Resistant Proteus mirabilis Harboring both blaNDM-1 and cfr genes  

作　　者：Meiqing Sun Xiuhong Yang Beibei Miao Jingyi Zhang Shuang Meng Zhe Feng Juan Li 

机构地区：[1]National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China [2]Wuqing District Centre for Disease Control and Prevention,Tianjin 301700,China [3]Baoshan Disease Control and Prevention,Baoshan 678000,Yunnan,China

出　　处：《Biomedical and Environmental Sciences》2024年第10期1208-1212,共5页生物医学与环境科学（英文版）

基　　金：the National Key Research and Development Program of China[grant number 2021YFC2302002]for financial support.

摘　　要：Proteus mirabilis is abundant in soil and water,and although it is part of the normal human intestinal flora(along with Klebsiella species and Escherichia coli),it is known to cause serious infections in humans,with a fatality rate of 20%-50%[1].Proteus mirabilis is intrinsically resistant to tetracycline,tigecycline,and colistin.The widespread and irregular use of antimicrobial agents,P.mirabilis antimicrobial resistance has mirabilis.They acquire antimicrobial resistance(AMR)by capturing plasmids,transposons,or other mobile elements harboring antimicrobial resistance genes.This mechanism allows the rapid selection and transmission of numerous AMR genes in clinical,veterinary,food production,transportation,and environmental settings.

关 键 词：LIS Proteus ant 

分 类 号：X172[环境科学与工程—环境科学]