基于《中国药典》的中药知识图谱构建与应用  

Construction and Application of Traditional Chinese Medicine Knowledge Graph Based on the Chinese Pharmacopoeia

作　　者：付涛涛 陈艳梅 李庆娜[2] 邵义明 苏国彬[4] 弓孟春 FU Taotao;CHEN Yanmei;LI Qingna;SHAO Yiming;SU Guobin;GONG Mengchun(Digital Health China Technologies Co.Ltd.,Beijing 100080,China;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;The First Dongguan Affiliated Hospital of Guangdong Medical University,Dongguan 523808,China;Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510000,China;Innovative Application Laboratory of Multimodal Data Fusion,Guangdong Medical University,Dongguan 523808,China)

机构地区：[1]神州医疗科技股份有限公司,北京100080 [2]中国中医科学院西苑医院,北京100091 [3]广东医科大学附属东莞第一医院,东莞523808 [4]广东省中医院,广州510000 [5]广东医科大学多模态数据融合创新应用实验室,东莞523808

出　　处：《医学信息学杂志》2024年第10期33-39,共7页Journal of Medical Informatics

基　　金：国家重点研发计划项目(项目编号:2023YFC2706305);国家中医药管理局监测统计中心自选课题(项目编号:YGZXKT2024013)。

摘　　要：目的/意义将电子信息领域的知识图谱技术引入中药术语研究,以生动的方式展示中药治疗作用与性味归经和中医疾病之间的辨证关系。方法/过程采用自上而下的本体构建方式在Protégé平台搭建中药本体顶层结构。以2020版《中国药典》一部为数据来源,抽取其中的中药信息,并整理各轴位信息、消歧和归一。借助Protégé平台创建实体和关系,以语义网络资源描述框架RDF数据格式输出中药三元组数据,并以Neo4j图数据库存储、展示,形成系统化的中药知识图谱。结果/结论完成基于《中国药典》的中药知识图谱构建,可通过数据统计分析、知识计量以及可视化图形绘制,充分揭示中药领域复杂的知识系统结构。Purpose/Significance To introduce the knowledge graph technology in the field of electronic information into the study of traditional Chinese medicine(TCM)terminology,and to demonstrate the dialectical relationship between the therapeutic effects of TCM and its nature,flavor,meridians and TCM diseases in a vivid way.Method/Process The top-down ontology construction method is adopted to build the top-level structure of TCM ontology on the Protégéplatform.Taking the 2020 edition of the Chinese Pharmacopoeia as the data source,the TCM information in the pharmacopoeia is split and extracted,and the information of each axis is sorted,disambiguated and normalized.With the help of the Protégéplatform,entities and relationships are created,and the TCM triple data is output in RDF data format.Finally,the Neo4j graph database is used to store and display the RDF data to form a systematic TCM knowledge graph.Result/Conclusion It mainly realizes the construction of the knowledge graph of TCM in the pharmacopoeia,and fully reveals the complex knowledge system structure in the field of TCM through data statistical analysis,knowledge measurement and drawing of visual graphics.

关 键 词：中药 《中国药典》 知识图谱 PROTÉGÉ Neo4j 

分 类 号：R-058[医药卫生]