3D全腔镜甲状腺全切术治疗分化型甲状腺癌患者的效果  

Effects of 3D total endoscopic thyroidectomy in treatment of patients with differentiated thyroid carcinoma

作　　者：张龙方 程守服 ZHANG Longfang;CHENG Shoufu(Second Department of General Surgery of Xinyang People’s Hospital,Xinyang 464100 Henan,China)

机构地区：[1]信阳市人民医院普外二科,河南信阳464100

出　　处：《中国民康医学》2024年第21期52-54,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察3D全腔镜甲状腺全切术治疗分化型甲状腺癌患者的效果。方法:选取2021年3月至2023年3月该院收治的64例分化型甲状腺癌患者进行前瞻性研究,按照随机数字表法将其分为对照组和观察组各32例。对照组行2D全腔镜甲状腺全切术治疗,研究组行3D全腔镜甲状腺全切术治疗。比较两组围术期指标(手术时间、术中出血量、淋巴结清扫数、术后引流时间、术后引流量)水平,手术前后炎性因子[白细胞计数(WBC)、白细胞介素-6(IL-6)、C反应蛋白(CRP)]水平,循环肿瘤细胞水平,以及并发症发生率。结果:研究组手术时间短于对照组,术中出血量少于对照组,差异均有统计学意义(P<0.05);两组淋巴结清扫数、术后引流时间、术后引流量比较,差异均无统计学意义(P>0.05);术后1 d,两组WBC、IL-6、CRP水平均高于术前,但组间比较,差异无统计学意义(P>0.05);术后7 d,两组循环肿瘤细胞水平均高于术前,但研究组低于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:3D全腔镜甲状腺全切术治疗分化型甲状腺癌患者可缩短手术时间,减少术中出血量,以及降低循环肿瘤细胞水平的效果优于2D全腔镜甲状腺全切术治疗。Objective:To observe effects of 3D total endoscopic thyroidectomy in treatment of patients with differentiated thyroid cancer.Methods:A prospective study was conducted on 64 patients with differentiated thyroid cancer admitted to this hospital from March 2021 to March 2023.According to the random number table method,they were divided into control group and observation group,32 cases in each group.The control group was treated with 2D total endoscopic thyroidectomy,while the study group was treated with 3D total endoscopic thyroidectomy.The perioperative indexes(operation time,intraoperative blood loss,number of lymph node dissected,postoperative drainage time,postoperative drainage volume)levels,the inflammatory factors[white blood cell count(WBC),interleukin-6(IL-6),C-reactive protein(CRP)]levels before and after the surgery,the circulating tumor cell levels,and the incidence of complications were compared between the two groups.Results:The operation time of the study group was shorter than that of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in the number of lymph node dissected,postoperative drainage time,and postoperative drainage volume between the two groups(P>0.05).1 day after the surgery,the levels of WBC,IL-6,and CRP in both groups were higher than before the surgery,but there were no statistically significant differences between the groups(P>0.05).7 days after the surgery,the levels of circulating tumor cells in the two groups were higher than those before the surgery,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:3D total endoscopic thyroidectomy for the patients with differentiated thyroid cancer can shorten the operation time,reduce the intra

关 键 词：分化型甲状腺癌 3D全腔镜甲状腺全切术 循环肿瘤细胞 炎性因子 并发症 

分 类 号：R736.1[医药卫生—肿瘤]