Effect of FTO on cardiac hypertrophy through the regulation of OBSCN expression  

作　　者：Lili Chen Yiheng Zhao Wenjing Wang Shuchen Zhang Xiang Zhou 

机构地区：[1]Central Laboratory,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215004,China [2]Department of Cardiology,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215004,China [3]Intensive Care Unit,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu215004,China

出　　处：《Genes & Diseases》2024年第6期84-87,共4页基因与疾病（英文）

基　　金：financially supported by the National Natural Science Foundation of China (No.82100251).

摘　　要：N^(6)-methyladenosine(m^(6)A)RNA methylation exerts significant functions in regulating various cardiovascular diseases.Following the recognition of the first m^(6)A demethylase,namely fat and obesity-associated protein(FTO),mounting evidence has shown that polymorphism of the FTO gene leads to an increased occurrence of cardiovascular-related risk factors including obesity,diabetes,and inflammation.

关 键 词：CARDIOVASCULAR OBESITY CARDIAC 

分 类 号：R542.2[医药卫生—心血管疾病]