盐酸哌甲酯缓释片与盐酸托莫西汀治疗儿童注意缺陷多动障碍的临床效果比较  

Comparison of the clinical effects of methylphenidate hydrochloride prolonged-release tablets and atomoxetine hydrochloride in the treatment of attention deficit hyperactivity disorder in children

作　　者：潘玉婷 PAN Yuting(Children's Health Department,Luoyang Maternal and Child Health Hospital,Luoyang 471000,China)

机构地区：[1]洛阳市妇幼保健院儿童保健科,河南洛阳471000

出　　处：《临床医学研究与实践》2024年第31期103-106,共4页Clinical Research and Practice

摘　　要：目的比较盐酸哌甲酯缓释片与盐酸托莫西汀治疗儿童注意缺陷多动障碍的临床效果。方法将2022年6月至2023年9月洛阳市妇幼保健院儿童保健科收治的56例注意缺陷多动障碍患儿纳入本次研究,根据治疗药物不同将其分为A组和B组,每组28例。A组给予盐酸哌甲酯缓释片治疗,B组给予盐酸托莫西汀治疗。比较两组的治疗效果。结果治疗前、后,两组的斯诺佩评估量表第四版(SNAP-Ⅳ)各维度及中国韦氏儿童智力量表(C-WISC)评分比较,差异无统计学意义(P>0.05)。两组的治疗总有效率比较,差异无统计学意义(P>0.05)。治疗前、后,两组的Conners父母症状问卷(PSQ)各维度评分比较,差异无统计学意义(P>0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论盐酸哌甲酯缓释片与盐酸托莫西汀治疗儿童注意缺陷多动障碍均可取得较佳疗效,快速消除患儿疾病症状。Objective To compare the clinical effects of methylphenidate hydrochloride prolonged-release tablets and atomoxetine hydrochloride in the treatment of attention deficit hyperactivity disorder in children.Methods From June 2022 to September 2023,56 children with attention deficit hyperactivity disorder admitted in the children's health department of Luoyang Maternal and Child Health Hospital were included in this study.According to different therapeutic drugs,the children were divided into group A and group B,with 28 cases in each group.The group A was treated with methylphenidate hydrochloride prolonged-release tablets,and the group B was treated with atomoxetine hydrochloride.The therapeutic effects of the two groups were compared.Results Before and after treatment,there were no significant differences in the scores of each dimension of the Swanson,Nolan,and Pelham,VersionⅣScale(SNAP-Ⅳ)and the Chinese Wechsler Intelligence Scale for Children(C-WISC)between the two groups(P>0.05).There was no significant difference in the total effective rate between the two groups(P>0.05).Before and after treatment,there were no significant differences in the scores of each dimension of Parent Symptom Questionnaire(PSQ)between the two groups(P>0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Methylphenidate hydrochloride prolonged-release tablets and atomoxetine hydrochloride in the treatment of children with attention deficit hyperactivity disorder can achieve better curative effect,quickly eliminate the symptoms of children with the disease.

关 键 词：儿童 注意缺陷多动障碍 盐酸哌甲酯缓释片 盐酸托莫西汀 

分 类 号：R749.94[医药卫生—神经病学与精神病学]