2016—2022年某精神病专科医院1181名女职工宫颈液基薄层细胞技术和人乳头状瘤病毒感染调查  

Investigation of Thinprep Cytology Test and Human Papillomavirus Infection in 1181 Female Workers in A Psychiatric Hospital from 2016 to 2022

作　　者：张冬红[1] 周新英[1] 黄和凤[1] 李雪娇 ZHANG Donghong;ZHOU Xinying;HUANG Hefeng;LI Xuejiao(Department of Hospital Infection Management,Ji'an Third People's Hospital,Ji'an 343000,China;Outpatient,Ji'an Central People's Hospital,Ji'an 343000,China)

机构地区：[1]吉安市第三人民医院医院感染管理科,吉安343000 [2]吉安市中心人民医院门诊部,吉安343000

出　　处：《中国医药指南》2024年第31期133-136,共4页Guide of China Medicine

摘　　要：目的分析精神病专科医院1181名女职工宫颈液基细胞学检查(TCT)和人乳头瘤病毒(HPV)的感染状况。方法选取精神病专科医院2016年1月至2022年12月在职的1181名女职工作为研究对象,所有人均行TCT与HPV检查,根据检查结果分析感染情况。结果1181名女职工HPV检测总阳性率为4.91%(58/1181),其中<30岁及40~50岁两个年龄段总阳性率高于其他年龄段(P<0.05)。TCT检测报告异常率为5.42%(64/1181),其中<30岁及40~50岁两个年龄段TCT检查总异常率高于其他年龄段(P<0.05)。初次性生活年龄<16岁女职工相较于初次性生活为其他年龄段女职工高危型HPV、低危型HPV、TCT异常的阳性率更高(P<0.05)。宫颈癌发病率逐年升高,且2021、2022年两个年份TCT与HPV阳性检出率相较于其他年份更高(P<0.05)。TCT分级中,高级别鳞状上皮内病变的高危型HPV阳性检出率高于低级别鳞状上皮内病变和非典型鳞状上皮细胞增生,非典型鳞状上皮细胞增生的HPV阴性率高于低级别鳞状上皮内病变和高级别鳞状上皮内病变(均P<0.05)。结论<30岁、41~50岁两个年龄段以及初次性生活年龄<16岁精神病专科医院女职工为易感人群,应加强对该部分女职工宫颈癌的防治工作,且宫颈癌发病率逐年升高,医院应更加重视医院女职工的宫颈癌预防健康宣教工作。Objective To analyze the infection status of Thinprep cytology test(TCT)and human papillomavirus(HPV)among 1181 female workers in psychiatric hospital.Methods A total of 1181 female workers in psychiatric hospital from January 2016 to December 2022 were selected as the study subjects.All workers underwent TCT examination and HPV examination,and the infection status was analyzed according to the examination results.Results The total positive rate of HPV test of 1181 female workers was 4.91%(58/1181),in which the total positive rate of<30 years old and 40-50 years old age groups was higher than that of other age groups(P<0.05).The abnormal rate of TCT test report was 5.42%(64/1181),in which the total abnormal rate of TCT test of<30 years old and 40-50 years old age groups was higher than that of other age groups(P<0.05).The positive rates of high-risk HPV,low-risk HPV,and TCT abnormalities were higher in female workers aged<16 years at the age of sexual debut compared with those in other age groups(P<0.05).The incidence rate of cervical cancer increased year by year,and the positive detection rate of TCT and HPV was higher in 2021 and 2022 compared with other years(P<0.05).In TCT grading,the positive detection rate of high-risk HPV was higher in high-grade squamous intraepithelial lesions than in low-grade squamous intraepithelial lesions and atypical squamous epithelial hyperplasia(P<0.05);the negative HPV rate of atypical squamous epithelial hyperplasia was higher than that of low-grade squamous intraepithelial lesions and atypical squamous epithelial hyperplasia,the negative rate of HPV-negative rate was higher than that of low-grade squamous intraepithelial lesions and high-grade squamous intraepithelial lesions(all P<0.05).Conclusions The female workers in psychiatric hospital with age<30 years old or 40-50 years old and first sexual life age<16 years old are susceptible population,and it is necessary to strengthen the prevention and treatment of cervical cancer in these female workers,and the incidence of cer

关 键 词：精神病专科医院 宫颈液基细胞学检查 人乳头瘤病毒 宫颈癌 

分 类 号：R737.33[医药卫生—肿瘤]