年轻与中老年女性乳腺癌的多模态超声对比分析  

Multimodal ultrasound analysis of breast cancer in young and middle-aged and elderly women

作　　者：龙星云 黄艳丽 闻宝杰 刘晗[3] 吴杰[3] 孔文韬 LONG Xingyun;HUANG Yanli;WEN Baojie;LIU Han;WU Jie;KONG Wentao(Nanjing Drum Tower Hospital,Drum Tower Clinical Medical College,Nanjing Medical University,Nanjing 210008,Jiangsu,China;Department of Special Diagnosis,Qinhuai Medical Treatment Area of East Theater General Hospital,Nanjing 210002,Jiangsu,China;Nanjing Drum Tower Hospital,Drum Tower Clinical Medi-cal College,Nanjing University,Nanjing 210008,Jiangsu,China)

机构地区：[1]南京医科大学鼓楼临床医学院,南京210008 [2]东部战区总医院秦淮医疗区特诊科,南京210002 [3]南京大学鼓楼临床医学院,南京210008

出　　处：《医学研究与战创伤救治》2024年第8期859-864,共6页Journal of Medical Research & Combat Trauma Care

摘　　要：目的比较年轻组(≤40岁)和中老年组(>40岁)女性乳腺癌患者的常规超声、超声弹性成像和超声造影特征,以找出两组乳腺癌患者的多模态超声差异特征,并探讨年轻乳腺癌患者的恶性风险是否被低估。方法收集2019年4月至2022年12月南京鼓楼医院乳腺外科收治的经手术或穿刺病理证实为乳腺癌的302例患者。根据年龄将患者分为两组:年轻组(≤40岁,n=42)、中老年组(>40岁,n=260)。对两组患者的常规超声、弹性成像及超声造影特征进行对比分析。结果年轻组乳腺癌患者的BI-RADS评分多集中在4 b(45.24%),中老年组乳腺癌患者BI-RADS评分则多集中在4c(45.77%);年轻乳腺癌患者的弹性评分主要集中在4分(52.38%)与3分(30.95%),中老年乳腺癌患者的弹性评分集中在4分(55.77%)与5分(24.23%),两组的BI-RADS评分与弹性评分比较差异有统计学意义(P<0.05)。两组造影增强后病灶形态、边界以及造影后预测病灶性质差异有统计学意义(P<0.001)。年轻组平均达到峰值时间显著低于中老年组(P<0.05)。结论中老年女性乳腺癌患者在BI-RADS分类、弹性评分及超声造影的恶性征象方面表现出更高的评分,但年轻患者的超声造影达峰时间较短,表明年轻乳腺癌患者的恶性风险被相对低估。Objective Compare the characteristics of traditional ultrasound,ultrasound elastography,and contrast-enhanced ultrasound in female breast cancer patients of the younger group(≤40 years old)and the middle-aged and elderly group(>40 years old).Identify the multimodal ultrasound differences between these two groups of breast cancer patients.Additionally,explore whether the malignancy risk in younger breast cancer patients has been underestimated.Methods We collected 302 cases of breast cancer patients confirmed by surgery or puncture pathology from the Breast Surgery Department of Nanjing Drum Tower Hospital between April 2019 and December 2022.We divided patients into two groups based on age:the young group(≤40 years old,n=42)and the mid‐dle-aged and elderly group(>40 years old,n=260).We conducted a comparative analysis of the conventional ultrasound,elastography,and contrast-enhanced ultrasound characteristics of both patient groups.Results The BI-RADS scores of young breast cancer pa‐tients were predominantly concentrated at category 4b(45.24%),while those of the middle-aged and elderly group were more frequent‐ly found at category 4c(45.77%).The ultrasonic elastography scores for young breast cancer patients mainly concentrated at scores of 4(52.38%)and 3(30.95%),whereas the middle-aged and elderly group showed scores focused at 4(55.77%)and 5(24.23%).A com‐parison of BI-RADS and ultrasonic elastography scores between the two groups demonstrated statistically significant differences(P<0.05).The morphological characteristics,boundaries,and post-con‐trast predictions of lesions also revealed statistically significant differences between the groups(P<0.001).The average time to peak enhancement for the young group was significantly lower than that of the middle-aged and elderly group(P<0.05).Conclusion Middle-aged and elderly female breast cancer patients showed higher scores in BI-RADS categorization,ultrasonic elastography scoring and malignant signs on contrast-enhanced ultrasound imaging.However,th

关 键 词：乳腺癌 多模态 超声弹性成像 超声造影 年轻女性 

分 类 号：R737.9[医药卫生—肿瘤]