大动脉粥样硬化型与小动脉闭塞型脑梗死患者认知障碍特点分析  

Characteristics of Cognitive Dysfunction in Patients with Large Artery Atherosclerosis and Small Artery Occlusion Cerebral Infarction

作　　者：吕晓培 康梅 李晓红 袁帅 卢海丽 陈娜 史万英 LYU Xiaopei;KANG Mei;LI Xiaohong;YUAN Shuai;LU Haili;CHEN Na;SHI Wanying(Department of Neurology,Shijiazhuang People's Hospital,Shijiazhuang 050000,China)

机构地区：[1]河北省石家庄市人民医院神经内科,050000

出　　处：《实用心脑肺血管病杂志》2024年第11期43-46,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：河北省卫生和计划生育委员会科研基金项目(20200156)。

摘　　要：目的探讨大动脉粥样硬化型与小动脉闭塞型脑梗死患者认知障碍的特点。方法回顾性选取2021年1月—2023年6月石家庄市人民医院收治的大动脉粥样硬化型脑梗死并认知障碍患者105例为大动脉粥样硬化型组,选取同时期石家庄市人民医院收治的小动脉闭塞型脑梗死并认知障碍患者110例为小动脉闭塞型组,收集两组患者的一般资料,采用简易智能精神状态检查量表(MMSE)评估两组患者认知功能。结果大动脉粥样硬化型组年龄≥60岁者占比高于小动脉闭塞型组(P<0.05)。小动脉闭塞型组MMSE总分及即刻记忆、语言功能、执行力维度得分低于大动脉粥样硬化型组(P<0.05)。结论与大动脉粥样硬化型脑梗死患者相比,小动脉闭塞型脑梗死患者认知障碍程度更严重,尤其是即刻记忆、语言功能、执行力方面。Objective To explore the characteristics of cognitive dysfunction in patients with large artery atherosclerosis and small artery occlusion cerebral infarction.Methods A total of 105 patients with large artery atherosclerosis cerebral infarction and cognitive dysfunction admitted to Shijiazhuang People's Hospital from January 2021 to June 2023 were retrospectively selected as the large artery atherosclerosis group,and 110 patients with small artery occlusion cerebral infarction and cognitive dysfunction admitted to Shijiazhuang People's Hospital during the same period were selected as the small artery occlusion group.General information of the two groups of patients was collected,and the cognitive function of the two groups was evaluated using the Mini-Mental State Examination(MMSE).Results The proportion of patients with age≥60 years old in the large artery atherosclerosis group was higheRthan that in the small artery occlusion group(P<0.05).The MMSE total score,immediate memory,language function,and executive force dimension scores in small artery occlusion group were loweRthan those in large artery atherosclerosis group(P<0.05).Conclusion Compared with patients with large artery atherosclerosis cerebral infarction,patients with small artery occlusion cerebral infarction have more severe cognitive impairment,especially in immediate memory,language function and executive force.

关 键 词：脑梗死 动脉粥样硬化 动脉闭塞性疾病 认知障碍 

分 类 号：R743.33[医药卫生—神经病学与精神病学]