Evaluation of the GATIS score for predicting prognosis in rectal neuroendocrine neoplasms  

作　　者：Yu-Ning Feng Li-Hong Liu Han-Wen Zhang 

机构地区：[1]Department of Radiology,The First Affiliated Hospital of Shenzhen University,Health Science Center,Shenzhen Second People’s Hospital,Shenzhen 518000,Guangdong Province,China

出　　处：《World Journal of Gastroenterology》2024年第42期4587-4590,共4页世界胃肠病学杂志（英文）

基　　金：Guangdong Medical Science and Technology Research Fund Project,No.A2024475.

摘　　要：The GATIS score,developed by Zeng et al,represents a significant advancement in predicting the prognosis of patients with rectal neuroendocrine neoplasms(RNENs).This study,which included 1408 patients from 17 major medical centres in China over 12 years,introduces a novel prognostic model based on the tumour grade,T stage,tumour size,age,and the prognostic nutritional index.Compared with traditional methods such as the World Health Organization classification and TNM staging systems,the GATIS score has superior predictive power for overall survival and progression-free survival.With a C-index of 0.915 in the training set and 0.812 in the external validation set,the GATIS score’s robustness and reliability are evident.The study’s use of a large,multi-centre cohort and rigorous validation processes underscore its significance.The GATIS score offers clinicians a powerful tool to accurately predict patient outcomes,guide treatment decisions,and improve follow-up strategies.This development represents a crucial step forwards in the management of R-NENs,addressing the complexity and variability of these tumours and setting a new benchmark for future research and clinical practice.

关 键 词：GATIS score Rectal neuroendocrine neoplasms Prognostic model Overall survival Multicentre study 

分 类 号：R735[医药卫生—肿瘤]