Improving early diagnosis of multiple endocrine neoplasia type 1 by assessing the gastrointestinal symptoms,hypercalcemia,and elevated serum gastrin  

作　　者：Tsvetelina Velikova Velik Lazarov 

机构地区：[1]Medical Faculty,Sofia University St.Kliment Ohridski,Sofia 1407,Bulgaria [2]Obstetrics and Gynaecology,Second Specialised Hospital for Obstetrics and Gynaecology“Sheynovo”,Sofia 1504,Bulgaria

出　　处：《World Journal of Gastroenterology》2024年第43期4677-4681,共5页世界胃肠病学杂志（英文）

基　　金：Supported by the European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.

摘　　要：Despite advancements in the field,early diagnosis of multiple endocrine neoplasia type 1(MEN1)remains unachievable.This letter to the editor highlighted the importance of carefully assessing gastrointestinal symptoms,hypercalcemia,and elevated serum gastrin levels,as suggested by Yuan et al in their paper.They focused on a patient with recurrent abdominal pain and diarrhea whose diagnostic path led to establishing a MEN1 diagnosis within a year.This emphasized the need for clinicians to consider MEN1 in patients with similar presentations,particularly when gastrointestinal symptoms persist or recur after discontinuation of proton pump inhibitors,especially knowing that early recognition and intervention are crucial for improving patient outcomes.

关 键 词：Multiple endocrine neoplasia type 1 Gastrointestinal symptoms HYPERCALCEMIA Early detection Early diagnosis 

分 类 号：R736[医药卫生—肿瘤]