Benefits and drawbacks of radiofrequency ablation via percutaneous or minimally invasive surgery for treating hepatocellular carcinoma  

作　　者：Ching-Lung Hsieh Cheng-Ming Peng Chun-Wen Chen Chang-Hsien Liu Chih-Tao Teng Yi-Jui Liu 

机构地区：[1]Department of Computer Science and Information Engineering,Feng Chia University,Taichung 40724,Taiwan [2]Department of Surgery,Chung Shan Medical University Hospital,Taichung 40201,Taiwan [3]School of Medicine,Chung Shan Medical University,Taichung 40201,Taiwan [4]Department of Radiology,Taichung Armed Forces General Hospital,Taichung 406,Taiwan [5]Department of Medical Imaging and Radiological Sciences,Central Taiwan University of Science and Technology,Taichung 406,Taiwan [6]Department of Radiology,School of Medicine,National Defense Medical Center,Taipei 11490,Taiwan [7]Department of Medical Imaging,China Medical University Hsinchu Hospital and China Medical University,Hsinchu 302,Taiwan [8]Institute of Nuclear Engineering and Science,National Tsing Hua University,Hsinchu 300,Taiwan [9]Department of Radiology,Nantou Hospital of the Ministry of Health and Welfare,Nantou 540,Taiwan [10]Master’s Program of Biomedical Informatics and Biomedical Engineering,Feng Chia University,Taichung 407,Taiwan [11]Department of Automatic Control Engineering,Feng Chia University,Taichung 407,Taiwan

出　　处：《World Journal of Gastrointestinal Surgery》2024年第11期3400-3407,共8页世界胃肠外科杂志（英文）

基　　金：Supported by Feng Chia University/Chung Shan Medical University,No.FCU/CSMU 112-001(to Peng CM and Liu YJ);Taiwan National Science and Technology Council,No.111-2314-B-035-001-MY3;Taichung Armed Forces General Hospital,No.107A42.

摘　　要：The management of early stage hepatocellular carcinoma(HCC)presents significant challenges.While radiofrequency ablation(RFA)has shown safety and effectiveness in treating HCC,with lower mortality rates and shorter hospital stays,its high recurrence rate remains a significant impediment.Consequently,achieving improved survival solely through RFA is challenging,particularly in retrospective studies with inherent biases.Ultrasound is commonly used for guiding percutaneous RFA,but its low contrast can lead to missed tumors and the risk of HCC recurrence.To enhance the efficiency of ultrasound-guided percutaneous RFA,various techniques such as artificial ascites and contrast-enhanced ultrasound have been developed to facilitate complete tumor ablation.Minimally invasive surgery(MIS)offers advantages over open surgery and has gained traction in various surgical fields.Recent studies suggest that laparoscopic intraoperative RFA(IORFA)may be more effective than percutaneous RFA in terms of survival for HCC patients unsuitable for surgery,highlighting its significance.Therefore,combining MIS-IORFA with these enhanced percutaneous RFA techniques may hold greater significance for HCC treatment using the MIS-IORFA approach.This article reviews liver resection and RFA in HCC treatment,comparing their merits and proposing a trajectory involving their combination in future therapy.

关 键 词：Percutaneous radiofrequency ablation Minimally invasive surgery Hepatocellular carcinoma Intraoperative radiofrequency ablation Contrast-enhanced ultrasound 

分 类 号：R735.7[医药卫生—肿瘤]