Emergence of the stromal vascular fraction and secretome in regenerative medicine  

作　　者：Ratan Kumar Choudhary Shanti Choudhary Abhishek Tripathi 

机构地区：[1]College of Animal Biotechnology,Guru Angad Dev Veterinary and Animal Sciences University,Ludhiana 141004,Punjab,India [2]Hilltop Animal Hospital,Palatine,IL 60074,United States

出　　处：《World Journal of Stem Cells》2024年第10期896-899,共4页世界干细胞杂志（英文）

基　　金：Supported by the Department of Biotechnology,Ministry of Science and Technology,Government of India,New Delhi,No.BT/PR42179/AAQ/1/814/2021;SERB-State University Research Excellence,No.SUR/2022/001952.

摘　　要：Recently,we read a mini-review published by Jeyaraman et al.The article explored the optimal methods for isolating mesenchymal stromal cells from adipose tissue-derived stromal vascular fraction(SVF).Key factors include tissue source,processing techniques,cell viability assessment,and the advantages/disadvantages of autologous vs allogeneic use.The authors emphasized the need for standardized protocols for SVF isolation,ethical and regulatory standards for cell-based therapy,and safety to advance mesenchymal stromal cell-based therapies in human patients.This manuscript shares our perspective on SVF isolation in canines.We discussed future directions to potentiate effective regenerative medicine therapeutics in human and veterinary medicine.

关 键 词：Stromal vascular fraction Mesenchymal stem cells Veterinary regenerative medicine Isolation procedures Canine model SECRETOME 

分 类 号：R318[医药卫生—生物医学工程]