Adipose-derived stem cells and knee osteoarthritis:New perspectives,old concerns  

作　　者：Eduardo B de Sousa JoséPaulo A Gabbi Filho Vinicius S Gameiro Leandra S Baptista 

机构地区：[1]Department of General and Specialized Surgery,Fluminense Federal University,Rio de Janeiro 24070-090,Brazil [2]Department of Orthopaedics,Quinta D’Or Hospital,Rio de Janeiro 20941-150,Brazil [3]Duque de Caxias Campus Prof Geraldo Cidade,Federal University of Rio de Janeiro,Rio de Janeiro 25065-050,Brazil

出　　处：《World Journal of Orthopedics》2024年第11期1001-1006,共6页世界骨科杂志（英文）

摘　　要：In this editorial,we comment on the paper by Muthu et al published in the recent issue of the journal.This editorial review focusses on the use of adipose-derived stem cells(ADSCs)in knee osteoarthritis treatment.We discuss the differences between the stromal vascular fraction and microfragmented adipose tissue and highlight the results of clinical studies comparing both treatments and the use of hyaluronic acid,platelet-rich plasma,and bone marrow aspirate concentrate.The use of expanded ADSCs is also discussed;moreover,concerns regarding treatment with ADSCs,particularly the heterogeneity of published studies and the need to standardize protocols to explore clinical potential is explored.

关 键 词：Adipose tissue Adipose-derived stem cells Stromal vascular fraction KNEE OSTEOARTHRITIS Microfragmented adipose tissue 

分 类 号：R684.3[医药卫生—骨科学]