Tilting homeostatic and dyshomeostatic microglial balance in health and disease:transforming growth factor-beta1 as a critical protagonist  

作　　者：Nicolas Hugues Yu Luo 

机构地区：[1]Department of Molecular and Cellular Biosciences,University of Cincinnati,Cincinnati,OH,USA [2]Neuroscience Graduate Program,University of Cincinnati,Cincinnati,OH,USA [3]Division of Immunobiology,Cincinnati Children’s Hospital Medical Center,University of Cincinnati College of Medicine,Cincinnati,OH,USA

出　　处：《Neural Regeneration Research》2025年第10期2895-2897,共3页中国神经再生研究（英文版）

基　　金：supported by NIH grants(R01NS125074,R01AG083164,and R21NS127177)(to YL).

摘　　要：Adult microglia,by continuously sensing changes in their environment and communicating with nearly all brain cell types,are considered to be the immune sentinels of the brain.In the healthy central nervous system(CNS),microglia display a unique molecular homeostatic signature(i.e.,Tmem119,P2ry12,Sall1,Siglech,Gpr34,and Hexb)(Figure 1A).

关 键 词：FIGURE signature CRITICAL 

分 类 号：R741[医药卫生—神经病学与精神病学]