头皮脑电高频振荡预测SeLECTS首次发作后的再发风险  

Prediction of recurrence risk after the first episode of SeLECTS using high-frequency scalp EEG oscillations

作　　者：车圆圆 黄志新[1] 陈辉[1] 查剑[1] 钟建民[1] 陈勇[1] Che Yuanyuan;Huang Zhixin;Chen Hui;Zha Jian;Zhong Jianmin;Chen Yong(Department of Neurology,Jiangxi Children's Hospital,Nanchang 330000,China)

机构地区：[1]江西省儿童医院神经内科,南昌330000

出　　处：《神经疾病与精神卫生》2024年第10期735-739,共5页Journal of Neuroscience and Mental Health

基　　金：江西省卫生健康委员会科技计划项目(20203679)。

摘　　要：目的探讨头皮脑电图高频振荡(HFOs)在预测伴中央颞区棘波的自限性癫痫(SeLECTS)首次发作后再发风险中的意义。方法回顾性选取2019年6月—2022年6月于江西省儿童医院住院或门诊就诊的114例首次发作的SeLECTS患儿为研究对象,检测其头皮脑电图HFOs,随访6个月,根据癫痫再发与否分为再发组和未再发组,比较两组患儿的HFOs检出率。结果114例SeLECTS患儿首次发作6个月内有42例(36.84%)出现癫痫再发。初诊时脑电图显示,无再发组中7例(9.72%)记录到HFOs,再发组中13例(30.95%)存在HFOs,两组比较差异有统计学意义(χ^(2)=6.786,P<0.05)。半年后复查脑电图,无再发组中5例(6.94%)记录到HFOs,再发组中11例(26.19%)存在HFOs,两组比较差异有统计学意义(χ^(2)=8.144,P<0.05)。结论SeLECTS患儿头皮脑电图检出HFOs可一定程度地提示癫痫首次发作再发率增加,且相对稳定。Objective To explore the significance of high-frequency oscillations(HFOs)in scalp electroencephalography in predicting the risk of recurrence of self-limited epilepsy with centro-temporal spikes(SeLECTS)with central temporal spikes after the first seizure.Methods A retrospective study was conducted on 114 children with first onset SeLECTS who were admitted or treated in the outpatient department of Jiangxi Children's Hospital from June 2019 to June 2022.Their scalp EEG HFOs were measured and followed up for 6 months.According to whether epilepsy recurs or not,they were divided into a recurrent group and a nonrecurrent group,and the detection rate of HFOs in the two groups of children was compared.Results Among 114 children with SeELECTS,42 cases(36.84%)experienced recurrent epilepsy within 6 months of their first seizure.At the initial diagnosis,HFOs were recorded in 7 cases(9.72%)of the non-recurrence group and 13 cases(30.95%)of the recurrence group on the EEG.The difference between the two was statistically significant(χ^(2)=6.786,P<0.05).Six months later,the EEG was re-examined,HFOs were recorded in 5 cases(6.94%)of the non-recurrence group and 11 cases(26.19%)of the recurrence group.The difference between the two groups was also statistically significan(tχ^(2)=8.144,P<0.05).Conclusions The detection of HFOs in scalp electroencephalography of children with SeLECTS can to some extent indicate an increased and relatively stable risk of recurrence of the first seizure.

关 键 词：癫痫 脑电图 高频振荡 伴中央颞区棘波的儿童良性癫痫 

分 类 号：R742.1[医药卫生—神经病学与精神病学]