囊腔型肺癌患者CT影像特征及其与甲状腺转录因子-1表达的关系研究  

CT imaging Characteristics and Their Relationship with Thyroid Transcription Factor-1 in Patients with Cystic Lung Cancer

作　　者：裴雪清 徐冲 郭双双[1] 张治业[1] PEI Xueqing;XU Chong;GUO Shuangshuang(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang,471000)

机构地区：[1]河南科技大学第一附属医院,471000

出　　处：《实用癌症杂志》2024年第11期1863-1866,共4页The Practical Journal of Cancer

摘　　要：目的探究囊腔型肺癌患者CT影像特征与甲状腺转录因子-1(TTF-1)的关系。方法回顾性分析123例囊腔型肺癌患者的临床资料,均行CT影像学检查。根据甲状腺转录因子-1(TTF-1)的表达情况分为TTF-1高表达组(n=58)以及TTF-1中/低表达组(n=65)。结果两组CT影像学特征比较结果显示,其中囊腔形态、是否存在血管造影征、支气管充气征、毛刺、肺部蜂窝征、磨玻璃征在两组中的占比存在统计学差异(P<0.05);腔内分隔、胸膜凹陷的病例数占比差异无统计学意义(P>0.05)。相关性分析结果显示,囊腔型肺癌患者CT影像学特征与TTF-1的表达不存在显著相关性(P>0.05)。结论TTF-1表达阳性患者与阴性患者的部分CT影像学特征的病例数占比存在差异,但相关性分析结果为不存在相关性。Objective To explore the relationship between CT imaging characteristics and thyroid transcription factor-1(TTF-1)in patients with cystic lung cancer.Methods A retrospective analysis was performed on the clinical data of 123 patients with cystic lung cancer,and all patients underwent CT imaging examination.According to TTF-1 expression,patients were divided into high expression group(n=58)and medium/low expression group(n=65).Results There were significant differences in cystic morphology,proportions of angiogram sign,air bronchogram sign,spicule sign,pulmonary honeycomb sign and ground-glass sign between the two groups(P<0.05),but there was no significant difference in proportions of intracystic division and pleural depression(P>0.05).The results of correlation analysis showed that there was no significant correlation between CT imaging characteristics and TTF-1 expression in patients with cystic lung cancer(P>0.05).Conclusion The proportions of some CT imaging characteristics are different in patients with positive expression of TTF-1 and those with negative expression.However,correlation analysis results show that there is no correlation.

关 键 词：囊腔型肺癌 状腺转录因子-1 CT影像学检查 病理表型 关联性 

分 类 号：R734.2[医药卫生—肿瘤]