儿童卵巢未成熟畸胎瘤临床诊治分析  

The management of immature ovarian teratomas in children

作　　者：祁艳卫[1] 仲智勇 高磊[1] 安艳晓 王若晗 QI Yanwei;ZHONG Zhiyong;GAO Lei;AN Yanxiao;WANG Ruohan(Second Dept of General Surgery,Hebei Provincial Children′s Hospital,Shijiazhuang 050031,China)

机构地区：[1]河北省儿童医院普外二科,石家庄050031

出　　处：《中国小儿血液与肿瘤杂志》2024年第5期373-375,378,共4页Journal of China Pediatric Blood and Cancer

摘　　要：目的 探讨儿童卵巢未成熟畸胎瘤的临床特点和治疗效果。方法 回顾性分析2015年6月—2020年6月我院收治6例儿童卵巢未成熟畸胎瘤的临床资料。中位年龄3.5岁。肿瘤位于左侧卵巢5例,右侧1例。3例表现为腹部肿物,2例为腹痛,1例为腹胀。术前检查所有患儿甲胎蛋白均增高,超声提示囊实性肿物伴钙化,腹部CT均为囊实性占位,含脂肪及钙化。结果 4例患儿行保留卵巢的肿瘤剜除术,2例行卵巢肿瘤切除术。病理结果回报均为未成熟畸胎瘤,1级2例,2级3例,3级1例。术后均未予化疗。随访23~67个月,均无瘤存活。结论 儿童卵巢未成熟畸胎瘤可行保留卵巢的肿瘤剜除术,术后需密切随访。Objective To investigate the clinical manifestations and surgical effectiveness of immature ovarian teratomas in children.Methods The clinical data of 6 children(middle age 3.5 years) with immature ovarian teratomas were retrospectively analyzed.There were 5 cases in left and 1 case in right side.The main presentation of 3 cases was abdominal mass,2 cases was abdominal pain,and 1 case was bloating.Abnormal alphafetoprotein(AFP)concentrations were detected in 6 patients before surgery.The preoperative ultrasound examinations were all cysts and solid mixed masses with calcification.The preoperative CT examinations of the abdomen were all cysts and solid masses,containing fat and calcification.Results Ovaries-sparing surgeries were done in 4 patients,and the other 2 patients underwent ovarian resection because of tumor severely invading ovaries.The pathological results of 6 patients were all immature teratomas,2 cases were grade 1,three cases were grade 2,and 1 case was grade 3.6 cases were followed up for 23-67 months.All of them survived.Conclusions Ovaries-sparing surgery was possible.Postoperative close follow-up should be done.

关 键 词：畸胎瘤 未成熟 儿童 卵巢 

分 类 号：R737.31[医药卫生—肿瘤]