丁苯酞注射液治疗脑梗死后失语的临床疗效及对语言功能的影响分析  

Analysis of the Clinical Effect of Butylphthalein Injection in the Treatment of Aphasia After Cerebral Infarction and its Influence on Speech Function

作　　者：林鸿盛 李东航[1] 蔡凯兵 LIN Hongsheng;LI Donghang;CAI Kaibing(Internal Medicine Department,Puning Overseas Chinese Hospital,Puning,Guangdong,515300,China)

机构地区：[1]普宁华侨医院内科,广东普宁515300

出　　处：《中外医疗》2024年第30期58-61,共4页China & Foreign Medical Treatment

摘　　要：目的 探讨丁苯酞注射液治疗脑梗死后失语患者的临床疗效及对语言功能的影响。方法 方便选取2020年4月—2022年9月普宁华侨医院内科收治的86例脑梗死后失语患者作为研究对象,依据不同治疗方法分为两组,对照组(n=43)采用常规对症治疗,治疗组(n=43)在对照组基础上加丁苯酞注射液治疗,分析对比两组患者汉语标准失语症评分(China Rehabilitation Research Center Aphasia Examination, CRRCAE)、治疗效果、失语程度(aphasia quotient, AQ)、血清相关指标。结果 治疗组治疗总有效率为95.35%(41/43),高于对照组的79.07%(34/43),差异有统计学意义(χ^(2)=5.108,P<0.05)。治疗组AQ改善有效率为100.00%(43/43)高于对照组的83.72%(36/43),差异有统计学意义(χ^(2)=5.599,P<0.05)。治疗前,两组患者CRRCAE评分比较,差异无统计学意义(P>0.05);治疗后,治疗组CRRCAE评分高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者血清学指标比较,差异无统计学意义(P>0.05);治疗后,治疗组血清学指标低于对照组,差异有统计学意义(P<0.05)。结论 丁苯酞注射液治疗脑梗死后失语患者可改善症状,恢复语言功能。Objective To investigate the clinical efficacy of butylphthalein injection in the treatment of aphasia after cerebral infarction and its influence on language function.Methods A total of 86 patients with aphasia after cerebral infarction admitted to the Internal Medicine Department of Puning Overseas Chinese Hospital from April 2020 to Sep⁃tember 2022 were conveniently selected as the study objects and divided into two groups according to different treat⁃ment methods.The control group(n=43)received conventional symptomatic treatment,and the treatment group(n=43)was treated with butadiphthalein injection on the basis of the control group.The China Rehabilitation Research Center Aphasia Examination(CRRCAE),therapeutic effect,aphasia quotient(AQ)and serum related indicators of the two groups were analyzed and compared.Results The total effective rate of treatment in the treatment group was 95.35%(41/43)higher than that of the control group 79.07%(34/43),the difference was statistically significant(χ^(2)=5.108,P<0.05).The AQ improvement rate in the treatment group was 100.00%(43/43)higher than that in the control group 83.72%(36/43),and the difference was statistically significant(χ^(2)=5.599,P<0.05).Before treatment,there was no sig⁃nificant difference in CRRCAE scores between the two groups(P>0.05);after treatment,the CRRCAE score of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).Be⁃fore treatment,there was no significant difference in serological indexes between the two groups(P>0.05).After treat⁃ment,serological indexes of the treatment group were lower than those of the control group,and the difference was sta⁃tistically significant(P<0.05).Conclusion Butylphthalein injection can improve symptoms and restore speech function in patients with aphasia after cerebral infarction.

关 键 词：脑梗死 语言功能 失语 丁苯酞注射液 

分 类 号：R743.3[医药卫生—神经病学与精神病学]