厚朴排气合剂联合莫沙必利治疗原发性胆汁反流性胃炎的临床疗效分析  

Analysis of clinical efficacy of Houpo Paiqi mixture combined with mosapride in the treatment of primary bile reflux gastritis

作　　者：廖山婴 黄霖琳 王蓓蓓 卢勉芬 郭映玲 布小玲 LIAO Shan-ying;HUANG Lin-lin;WANG Bei-bei(Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,China)

机构地区：[1]南方医科大学附属广东省人民医院,广东省医学科学院消化内科,510080

出　　处：《中国实用医药》2024年第20期152-155,共4页China Practical Medicine

摘　　要：目的探讨厚朴排气合剂联合莫沙必利治疗原发性胆汁反流性胃炎的临床效果。方法160例原发性胆汁反流性胃炎患者,用随机数字表法分为对照组和研究组,每组80例。对照组应用莫沙必利治疗,研究组应用莫沙必利联合厚朴排气合剂治疗。比较两组患者临床疗效、胃镜下疗效及胃电节律、不良反应发生情况。结果研究组患者临床总有效率96.25%高于对照组的85.00%,差异有统计学意义(P<0.05)。研究组患者胃镜下总有效率95.00%高于对照组的78.75%,差异有统计学意义(P<0.05)。治疗后,两组患者胃窦、胃体餐后餐前主功率比值均高于本组治疗前,且研究组患者胃窦、胃体餐后餐前主功率比值分别为(1.31±0.22)、(1.29±0.20),高于对照组的(1.17±0.16)、(1.18±0.15),差异有统计学意义(P<0.05)。两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论应用莫沙必利联合厚朴排气合剂治疗原发性胆汁反流性胃炎患者效果十分显著,值得推广应用。Objective To explore the clinical effect of Houpo Paiqi mixture combined with mosapride in the treatment of primary bile reflux gastritis.Methods 160 patients with primary bile reflux gastritis were divided into a control group and a study group by random number table method,with 80 cases in each group.The control group was treated with mosapride,and the study group was treated with mosapride combined with Houpo Paiqi mixture.The clinical efficacy,efficacy under gastroscope,gastric electric rhythm and the occurrence of adverse reactions between the two groups.Results The total clinical effective rate of 96.25%in the study group was higher than 85.00%in the control group,and the difference was statistically significant(P<0.05).The total effective rate under gastroscopy in the study group was 95.00%,which was higher than 78.75%in the control group,and the difference was statistically significant(P<0.05).After treatment,the postprandial and preprandial main power ratios of the gastric sinus and gastric body in both groups were higher than those before treatment in this group;the postprandial and preprandial power ratios of the gastric sinus and gastric body were(1.31±0.22)and(1.29±0.20)in the study group,which were higher than(1.17±0.16)and(1.18±0.15)in the control group;the difference was statistically significant(P<0.05).The difference in the incidence of adverse reactions between the two groups was not statistically significant(P>0.05).Conclusion The application of mosapride combined with Houpo Paiqi mixture has a very significant effect in the treatment of patients with primary bile reflux gastritis,and is worthy of popularization and application.

关 键 词：原发性胆汁反流性胃炎 厚朴排气合剂 莫沙必利 疗效 胃电节律 

分 类 号：R573.3[医药卫生—消化系统]