The mutual regulation between the pattern recognition receptor OsCERK1 and the E3 ubiquitin ligase OsCIE1 controls induction and homeostasis of immunity  

模式相关受体OsCERK1与E3泛素化连接酶OsCIE1相互调节以维持免疫稳态

作　　者：Qiong Wang Yoji Kawano 王琼;Yoji Kawano

机构地区：[1]College of Plant Protection,Yangzhou University,Yangzhou 225009,China [2]Institute of Plant Science and Resources,Okayama University,Okayama 710-0046,Japan

出　　处：《Science Bulletin》2024年第20期3172-3175,共4页科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China(32101734 and 32311540012);JSPS KAKENHI(20H02988,21H05035,23H02213,23K26906,23K18030,24H01371);JSPS Bilateral Programs(JPJSBP20237408);Ohara foundation;the Yakumo Foundation for Environmental Science;the Ryobi Teien Memory Foundation;the NOVARTIS Foundation(Japan)for the Promotion of Science;the Naito foundation;the Joint Usage/Research Center;the Institute of Plant Science and Resources。

摘　　要：Plants have a multilayered immune system that includes pattern-triggered immunity(PTI)and effector-triggered immunity(ETI)to cope with pathogen attacks[1].PTI,also known as basal innate immunity,is initiated by the perception of microbe-/pathogen-associated molecular patterns(MAMPs/PAMPs)by pattern recognition receptors(PRRs).PRRs are cell surface-localized kinase complexes comprising receptor-like kinases(RLKs)and receptorlike proteins(RLPs).The majority of characterized RLKs structurally possess a variable extracellular domain(ECD),a single transmembrane(TM)region,and an intracellular kinase domain(KD),whereas RLPs lack an intracellular KD.The three most prevalent types of PRR ectodomains are leucine-rich repeats(LRR),multiple lysin motifs(LysM),and lectin domains.In the early stages of pathogen infection,PRR signaling is rapidly activated and triggers a series of immune responses,such as ROS bursts,callose deposition,and pathogenesis-related(PR)gene expression,to repel pathogenic microorganisms.

关 键 词：IMMUNITY PATTERN mutual 

分 类 号：R392[医药卫生—免疫学]