Functional PEGylated bacteria reinforce the intestinal mucosal barrier by effective mucus-penetration  

功能性聚乙二醇化细菌通过有效的粘液渗透增强肠粘膜屏障

作　　者：Xinyuan Yang Zhonglin Fang Luoran Shang 杨心远;方仲林;商珞然

机构地区：[1]Shanghai Xuhui Central Hospital,Zhongshan-Xuhui Hospital,and the Shanghai Key Laboratory of Medical Epigenetics,the International Co-laboratory of Medical Epigenetics and Metabolism(Ministry of Science and Technology),Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,China

出　　处：《Science Bulletin》2024年第19期2964-2966,共3页科学通报（英文版）

基　　金：supported by the National Key Research and Development Program of China(2020YFA0908200);the National Natural Science Foundation of China(32271383).

摘　　要：Recently,the intestinal mucosal barrier has attracted considerable attention from the scientific community.With the in-depth exploration of this barrier,it has become increasingly clear that the mucosal barrier is a complicated system consisting of multiple components.In general,the intestinal mucosal barrier mainly consists of intestinal epithelial cells covered with a highly viscous gellike layer containing symbiotic microorganisms and rich antimicrobial agents that can effectively protect the human body from the invasion of harmful microorganisms and toxins.

关 键 词：MUCOSAL INVASION barrier 

分 类 号：R574[医药卫生—消化系统]