外周血单核细胞与高密度脂蛋白胆固醇比值与急性脑梗死关系的研究进展  

Research advances in the association between peripheral blood monocyte to high-density lipoprotein cholesterol ratio and acute cerebral infarction

作　　者：郝晨宇 栾慧文 陈学丛 张彬 田雨禾 时宝林 HAO Chenyu;LUAN Huiwen;CHEN Xuecong;ZHANG Bin;TIAN Yuhe;SHI Baolin(School of Clinical Medicine,Shandong Second Medical University,Weifang 261053,China)

机构地区：[1]山东第二医科大学临床医学院,山东潍坊261053 [2]潍坊市人民医院神经内科

出　　处：《精准医学杂志》2024年第6期552-555,559,共5页Journal of Precision Medicine

基　　金：潍坊市卫生健康委员会科研项目(WFWSJK-2020-193)。

摘　　要：急性脑梗死是危害公民生命健康的最主要疾病之一。炎症反应与急性脑梗死的发生发展进程密切相关,炎性标志物水平的高低可反映炎症反应的严重程度。外周血单核细胞与高密度脂蛋白胆固醇比值(MHR)作为近年来新应用的代表炎症反应程度的指标,受到广泛关注。本文就外周血MHR与急性脑梗死的高危因素、风险预测、早期功能恶化、严重程度评估、出血转化及预后等方面的关系进行综述。Acute cerebral infarction is one of the most important diseases that endanger the life and health of citizens.Inflammatory response is closely associated with the development and progression of acute cerebral infarction,and the levels of inflammatory markers can reflect the severity of inflammation.In recent years,monocyte to high-density lipoprotein cholesterol ratio(MHR)has attracted wide attention as a newly applied indicator for the degree of inflammatory response.This article reviews the association between peripheral blood MHR and acute cerebral infarction in terms of high-risk factors,risk prediction,early functional deterioration,severity assessment,hemorrhagic transformation,and prognosis.

关 键 词：脑梗死 单核细胞 胆固醇 HDL 综述 

分 类 号：R743.33[医药卫生—神经病学与精神病学]