老年结直肠癌患者术后肠梗阻发生的危险因素  

Risk Factor Analysis of Postoperative Intestinal Obstruction in Elderly Patients with Colorectal Cancer

作　　者：丁亚艳 薛慧[1] 张宜南[1] 朱珠 朱学婷 王爱华[1] 杨柳[1] 司呈帅 许畅[1] Ding Yayan;Xue Hui;Zhang Yinan;Zhu Zhu;Zhu Xueting;Wang Aihua;Yang Liu;Si Chengshuai;Xu Chang(Department of Colorectal Surgery,Jiangsu Cancer Hospital,Affiliated Cancer Hospital of Nanjing Medical University,Nanjing 210009)

机构地区：[1]江苏省肿瘤医院南京医科大学附属肿瘤医院结直肠外科,南京210009

出　　处：《国际老年医学杂志》2024年第6期685-688,共4页International Journal of Geriatrics

基　　金：国家自然科学基金委员会资助项目(面上项目)(82072704);江苏省肿瘤医院科技发展基金项目(ZH202307)。

摘　　要：目的 探讨老年结直肠癌患者术后肠梗阻发生的危险因素。方法 选取2021年1月—2024年2月江苏省肿瘤医院收治的300例老年结直肠癌根治术患者进行回顾性分析,按照术后30 d内有无肠梗阻发生分为发生组(40例)与未发生组(260例)。收集患者的临床资料进行比较,采用多因素logistic回归模型分析影响术后肠梗阻发生的危险因素。结果 两组的年龄、性别、吸烟史、肿瘤部位、TNM分期及腹部手术史比较,差异均有统计学意义(P<0.05)。多因素logistic回归分析结果显示,年龄≥70岁、男性、直肠肿瘤、TNM分期Ⅲ期均为老年结直肠癌患者术后30 d内发生肠梗阻的独立危险因素(P<0.05)。结论 年龄≥70岁、男性、直肠肿瘤、TNM分期Ⅲ期的老年结直肠癌患者术后30 d内发生肠梗阻风险较大,临床应加以关注。Objective To investigate the risk factor of postoperative intestinal obstruction in elderly patients with colorectal cancer.Methods A retrospective analysis was conducted on 300 elderly patients who underwent radical resection for colorectal cancer admitted to Jiangsu Cancer Hospital from January 2021 to February 2024.Patients were divided into an occurrence group(40 cases)and a non occurrence group(260 cases)based on whether intestinal obstruction occurred within 30 days after surgery.Clinical data were collected and compared between the two groups.Multivariate logistic regression analysis model was performed to identify risk factors for postoperative intestinal obstruction.Results The differences in age,gender,smoking history,tumor location,TNM staging,and abdominal surgery history between the two groups were statistically significant(P<0.05).Multivariate logistic regression analysis revealed that age≥70 years,male gender,rectal tumor,and TNM stageⅢwere independent risk factors for the development of intestinal obstruction within 30 days postoperatively in elderly colorectal cancer patients(P<0.05).Conclusion Elderly patients with colorectal cancer aged≥70 years,male,rectal tumors,TNM stagesⅢhave a higher risk of developing intestinal obstruction within 30 days after surgery,and clinical attention should be paid.

关 键 词：结直肠癌 肠梗阻 危险因素 

分 类 号：R735.34[医药卫生—肿瘤]