增稠组件流变性比较及其稠度分级试验  

Rheological Comparison of Thickening Component Formulations and Consistency Grading Test

作　　者：吴帅 童海兵 WU Shuai;TONG Haibing(Hangzhou Zejian Pharmaceutical Technology Co.,Ltd.,Hangzhou 310020)

机构地区：[1]杭州泽健医药科技有限公司,杭州310020

出　　处：《食品工业》2024年第10期76-81,共6页The Food Industry

摘　　要：吞咽障碍患者由于吞咽生理机制受损,易引发误吸、肺部感染等风险,而增稠组件可以改变流体的质构,使其黏度发生改变,从而帮助患者将食物安全有效地输送至体内。通过对特殊医学用途增稠组件配方粉的黏度、触变性、黏弹性、温度响应等流变学特性的分析,比较试验品与其同类竞品(Thicken Up Clear、奥特顺咽和Thicken Up)之间的差异性,同时也为试验品在不同介质中的稠度分级提供依据。结果发现:与Thicken Up Clear、奥特顺咽和Thicken Up相比,同稠度级别下,试验品的屈服应力(σ0)8.52 Pa低于Thicken Up Clear(9.03 Pa)和奥特顺咽(14.60 Pa);热稳定性方面,70℃对试验品的黏度影响并不大;根据黏度结果,试验品在水体系下,低、中和高稠型的冲调量分别1.5,3.0和6.0 g/100 mL;在橙汁和蛋白粉体系下,低、中和高稠型的冲调量分别0.75,1.5和3.0 g/100mL。试验表明:该配方的增稠效果与临床成熟的同类产品无异,服用试验品吞咽更轻松、安全性更高。研究为试验品在临床及实际生活中的应用提供依据。Patients with dysphagia are prone to aspiration,lung infection and other risks due to the im-paired physiological mechanism of swallowing,and the thickening component can change the texture of the fluid to change its viscosity,thereby helping patients to safely and effectively deliver food to the body.The viscosity,thixotropy,viscoelasticity,temperature response and other rheological properties of thickening component formulations for special medical applications were analyzed,aiming to compare the difference between this product and its competitors(Thicken Up Clear,Otter Paropharynx and Thicken Up),and to provide a basis for the consistency classification of this product in different media.The results showed that the yield stress(σ0)8.52 Pa of the product was lower than that of Thicken Up Clear(9.03 Pa)and AoTeShunYan(14.60 Pa)under the same consistency grade compared with Thicken Up Clear,AoTeShunYan and Thicken Up;In terms of thermal stability,70℃had little effect on the viscosity of the product.According to the viscosity results,the brew amounts of low,medium and high viscosity types of the product in water system were 1.5,3.0 and 6.0 g/100 mL,respectively.In orange juice and protein powder system,the brew amounts of low,medium and high consistency type was 0.75,1.50 and 3.00 g/100 mL,respectively.This test showed that the thickening effect of the formula was no different from that of clinically mature similar products,and swallowing of the product was easier and safer.At the same time,it provided the basis for the application of the product in clinical and practical life.

关 键 词：增稠组件 吞咽障碍 流变性 稠度分级 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]