肺结核与肺癌共病的机制研究及启示  

Pathogenesis of comorbidity between pulmonary tuberculosis and lung cancer

作　　者：梁艳[1] 吴雪琼[1] Liang Yan;Wu Xueqiong(Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment,Institute of Tuberculosis Research,Senior Department of Tuberculosis,the Eighth Medical Center of PLA General Hospital,Beijing 100091,China)

机构地区：[1]解放军总医院第八医学中心,结核病医学部研究所,结核病诊疗新技术北京市重点实验室,北京100091

出　　处：《中华结核和呼吸杂志》2024年第11期1042-1047,共6页Chinese Journal of Tuberculosis and Respiratory Diseases

摘　　要：肺结核和肺癌都是临床常见疾病,均为严重的公共卫生问题。两种疾病在发生、发展过程中在多因素作用下相互促进可形成共病。近年来肺癌与肺结核共病的机制研究及诊疗方法的探索均取得一定进展,但仍存在一些不明确的机制需进一步探索。本文将简介肺结核与肺癌共病的流行病学特征,重点概述共病的潜在发病机制,提出当前面临的挑战并展望未来可能的研究方向,为共病诊疗新手段的研发提供思路。Pulmonary tuberculosis and lung cancer are both common clinical diseases and serious public health problems.These two diseases can form a comorbidity by promoting each other under the influence of multiple factors during their occurrence and development.In recent years,some progress has been made in understanding the mechanism and exploring the diagnosis and treatment of comorbidity.However,there are still some unclear mechanisms that require further investigation.This paper briefly introduces the epidemiological characteristics of the comorbidity between pulmonary tuberculosis and lung cancer,and focuses on the potential pathogenesis of the comorbidity.It highlights the current challenges and looks ahead to potential future research directions,including suggestions for the development of new diagnostic and therapeutic strategies for the comorbidity.

关 键 词：共病 肺结核 展望未来 流行病学特征 肺癌 发病机制 公共卫生问题 临床常见疾病 

分 类 号：R734.2[医药卫生—肿瘤] R521[医药卫生—临床医学]