膝关节腔内及周围痛点注射富血小板血浆联合微创手术治疗膝关节骨性关节炎患者的临床效果  

Clinical Effect of Intra-Articular and Peri-Knee Pain Points Injection of Platelet Rich Plasma Combined with Minimally Invasive Surgery for Patients with Knee Osteoarthritis

作　　者：刘志鹏 廉波 LIU Zhipeng;LIAN Bo(Department of Orthopedics,Yantai Port Hospital,Yantai 264000,China)

机构地区：[1]山东省烟台海港医院骨科,山东烟台264000

出　　处：《中国伤残医学》2024年第14期92-95,共4页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨膝关节腔内及周围痛点注射富血小板血浆(PRP)联合微创手术治疗膝关节骨性关节炎(KOA)患者的临床效果。方法:选取2021年9月—2023年9月烟台海港医院收治的96例KOA患者为研究对象,按随机数字表法将其分为对照组和研究组,各48例。对照组采用微创手术治疗,研究组在对照组基础上联合膝关节腔内及周围痛点注射PRP治疗。比较两组膝关节功能、疼痛程度、日常生活能力及生活质量。结果:术后3个月,研究组西安大略省和麦克马斯特大学骨关节炎指数各维度评分及总分分别为(17.53±2.14)分、(2.61±0.42)分、(0.65±0.12)分、(20.79±3.24)分,均低于对照组的(23.44±3.15)分、(3.62±0.54)分、(1.02±0.22)分、(28.08±3.62)分,差异均有统计学意义(P<0.05)。术后3个月,研究组疼痛视觉模拟评分为(1.12±0.14)分,低于对照组的(1.46±0.16)分,Barthel指数评分为(88.96±5.32)分,高于对照组的(80.37±5.26)分,差异均有统计学意义(P<0.05)。术后3个月,研究组世界卫生组织生活质量简表各领域评分分别为(88.96±5.63)分、(89.68±5.54)分、(90.88±4.26)分、(92.41±4.15)分,均高于对照组的(80.69±5.47)分、(82.41±5.35)分、(84.31±5.37)分、(85.43±5.31)分,差异均有统计学意义(P<0.05)。结论:膝关节腔内及膝周围痛点注射PRP联合微创手术治疗KOA患者的效果更佳,有助于缓解疼痛,改善膝关节功能和生活质量,提高日常生活能力。Objective:To investigate the Clinical effect of intra-articular and peri knee pain points injection of platelet rich plasma(PRP)combined with minimally invasive surgery for patients with knee osteoarthritis(KOA).Methods:A total of 96 KOA patients admitted to Yantai Port Hospital from September 2021 to September 2023 were selected as the study objects,and were divided into a control group and a study group according to random number table method,with 48 cases in each group.The control group was treated with minimally invasive surgery,and the study group was treated with intra-articular and peri knee pain points injection PRP.Knee function,pain degree,daily living ability and quality of life were compared between the two groups.Results:Three months after surgery,the score and total score of Western Ontario and McMaster University Osteoarthritis Index in the study group were(17.53±2.14)points,(2.61±0.42)points,(0.65±0.12)points and(20.79±3.24)points,respectively,which were lower than(23.44±3.15)points,(3.62±0.54)points,(1.02±0.22)points and(28.08±3.62)points in the control group,the differences were statistically significant(P<0.05).Three months after surgery,the pain Visual Analogue Scale score of the study group was(1.12±0.14)points,which was lower than(1.46±0.16)points of the control group,and the Barthel Index score was(88.96±5.32)points,which was higher than(80.37±5.26)points of the control group,with statistical significance(P<0.05).Three months after surgery,the scores of the World Health Organization Quality of Life Summary Table were(88.96±5.63)points,(89.68±5.54)points,(90.88±4.26)points,(92.41±4.15)points,respectively,which were higher than(80.69±5.47)points,(82.41±5.35)points,(84.31±5.37)points and(85.43±5.31)points in the control group,the differences were statistically significant(P<0.05).Conclusion:Intra-articular and peri knee pain points injection of PRP combined with minimally invasive surgery is more effective in the treatment of KOA patients,which can accelerate pain relief,be

关 键 词：膝关节骨性关节炎 富血小板血浆 微创手术 膝关节功能 

分 类 号：R743[医药卫生—神经病学与精神病学]