中国胃食管反流病的诊疗进展  

Advances in the Diagnosis and Treatment of Gastroesophageal Reflux Disease in China

作　　者：庄茜钧 江典轩 肖英莲[1] Qianjun Zhuang;Dianxuan Jiang;Yinglian Xiao(Department of Gastroenterology,First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]中山大学附属第一医院消化内科,广州510080

出　　处：《中华胃食管反流病电子杂志》2024年第2期75-80,共6页Chinese Journal Of Gastroesophageal Reflux Disease(Electronic Edition)

摘　　要：胃食管反流病(GERD)是常见的慢性消化系统疾病。在中国,GERD的患病率高达8.7%。由于GERD临床表现多样化,其诊断对于临床医师是一大挑战。中国指南提出洛杉矶B级及以上食管炎或食管酸暴露百分比超过4%可确诊GERD。另外,尽管抑酸药物是GERD的一线治疗方式,但仍有高达50%的患者服药后症状无法有效缓解。药物治疗无效的患者通常选择接受内镜下抗反流手术,但是一部分患者术后仍需服用抗反流药物甚至接受二次手术以控制GERD症状。本文总结了目前中国GERD的诊断和治疗现状,为临床医师提供一定参考。Gastroesophageal reflux disease(GERD)is one of the most common chronic gastrointestinal disorders.The prevalence of GERD in China is 8.7%.Due to the diverse manifestations,the diagnosis of GERD is a challenge for clinicians.Chinese guideline proposed that patients with Los Angeles grade B/C/D esophagitis or acid exposure time>4%could be diagnosed as GERD.Although acid suppressive therapy is the first-line treatment for GERD,up to 50%of patients did not report effective symptom relief despite medications.Such patients typically undergo endoscopic anti-reflux surgery,but some still need to take anti-reflux medication or even undergo a secondary surgery to control GERD symptoms.This article summarized the current status of diagnosis and treatment of GERD in China,offering valuable insights for clinical physicians.

关 键 词：胃食管反流病 诊断 治疗 

分 类 号：R571[医药卫生—消化系统]