Current status and perspectives in environmental oncology  

作　　者：Jie Liu Ting Gan Wenbiao Hu Yumin Li 

机构地区：[1]Department of Tumor Surgery,General Surgery,Gansu Provincial Key Laboratory of Gastrointestinal Tumor,Key Laboratory of Environmental Oncology in Gansu Province,Lanzhou University Second Hospital,Lanzhou,Gansu,China [2]Center for Digestive System Tumor Transformation and Innovation Engineering,Environmental Oncology Center,Lanzhou University,Lanzhou,Gansu,China [3]Ecosystem Change and Population Health Research group,School of Public Health and Social Work,The Institute of Health and Biomedical Innovation,Queensland University of Technology,Brisbane,Australia

出　　处：《Chronic Diseases and Translational Medicine》2024年第4期293-301,共9页慢性疾病与转化医学（英文版）

基　　金：The Fundamental Research Funds for the Central Universities(Grant/Award Number:lzujbky-2022-sp08);Project of Gansu Provincial Department of Education(Grant/Award Number:2021jyjbgs-02);New Models of Environmental Cancer Prevention and Treatment and Key Technologies of Precision Diagnosis and Treatment(Grant/Award Number:22JR9KA002);China Scholarship Council(CSC)(Grant/Award Number:202306180074);Medical Innovation and Development Project of Lanzhou University(Grant/Award Numbers:lzuyxcx-2022-154,lzuyxcx-2022-141);Project of Gansu Provincial Development and Reform Commission(Grant/Award Number:2020-2022);Major Science and Technology Project of Gansu Province(Grant/Award Number:20zd7fa003)。

摘　　要：Cancer stands as a leading global cause of death,with its etiology characterized by complexity and multifaceted factors.Growing research indicates a strong correlation between environmental factors and cancer incidence,underscoring the critical importance of intervening in environmental risk factors to mitigate cancer occurrence.Despite this,specialized research institutions focusing on the intersection of environment and cancer remain scarce,with global investment in cancer prevention significantly trailing behind efforts in diagnosis and treatment.Against the backdrop of rapid global climate change,industrialization,urbanization,aging populations,and the globalization of lifestyles,we proposed the concept ofEnvironmental Oncology(EO)to address these challenges.We discussed the rationale and necessity of developing EO and presented a comprehensive research framework focusing on cancer prevention and treatment.Future EO research will aim to identify cancer causes and implement early prevention strategies using advanced scientific technologies and methods.By emphasizing multidisciplinary collaboration and integrating molecular biology at the micro level,EO will explore the relationship between external and internal environments and cancer.EO will identify potential therapeutic targets by studying the pathways through which environmental exposures lead to carcinogenesis.EO will develop early warning systems and disseminate research findings by collecting big data,employing robust statistical models,and establishing research centers.

关 键 词：cancer CLIMATE DISPARITIES environment environmental oncology PREVENTION 

分 类 号：R730[医药卫生—肿瘤]