胶原蛋白海绵用于种植体周角化龈增量的临床效果观察  

Clinical evaluation of collagen sponge for augmenting keratinized gingiva around dental implants

作　　者：钟志通 黄忞[1] 王婧 沈溱原 吴润发[1] Zhong Zhitong;Huang Min;Wang Jing;Shen Qinyuan;Wu Runfa(The Affiliated Stomatological Hospital of Nanchang University&The Key Laboratory of Oral Biomedicine,Jiangxi Province&Jiangxi Province Clinical Research Center for Oral Diseases,Nanchang 330006,China)

机构地区：[1]南昌大学附属口腔医院、江西省口腔生物医学重点实验室、江西省口腔疾病临床医学研究中心,330006

出　　处：《中国口腔种植学杂志》2024年第5期474-479,共6页Chinese Journal of Oral Implantology

基　　金：江西省应用研究培育计划(20212BAG70018)。

摘　　要：目的评价胶原蛋白海绵用于种植体周角化龈增量的临床效果。方法14例患者的16个手术位点随机分为胶原蛋白海绵组和游离龈移植物组进行角化龈增量。在基线、术后即刻、6周和12周测量角化龈宽度、软组织厚度变化、颜色差异,视觉模拟评分法(visual analogue scale,VAS)评分疼痛。结果在12周时,游离龈移植物组与胶原蛋白海绵组角化龈宽度分别为(5.81±0.75)mm和(3.50±0.53)mm(P<0.001),软组织厚度的变化量分别为(0.83±0.44)mm和(0.04±0.07)mm(P<0.05),颜色差异数值分别为130.86±53.99和34.13±31.77(P<0.05),VAS疼痛评分分别为(5.13±1.25)分和(1.88±1.13)分(P<0.001),手术时间分别为(38.17±4.56)min和(21.17±3.72)min(P<0.01),均具有统计学差异。结论胶原蛋白海绵可用于种植体周角化龈增量,与游离龈移植物相比,可以获得更佳的美学效果,减少手术时间,并避免由于开辟供区带来的额外创伤。Objective To evaluate the clinical efficacy of collagen sponge in augmenting keratinized gingiva around dental implants.Methods Fourteen patients with 16 surgical sites were randomly assigned to either the collagen sponge group or the free gingival graft group for keratinized gingiva augmentation.The width of keratinized tissue(WKT),soft tissue thickness(ST),color difference,and visual analogue scale(VAS)pain scores were measured at baseline,immediately after surgery,and at 6 weeks and 12 weeks postoperatively.Results At 12 weeks,the WKT was(5.81±0.75)mm and(3.50±0.53)mm(P<0.001),and the change in soft tissue thickness was(0.83±0.44)mm and(0.04±0.07)mm(P<0.05)in the free gingival graft and collagen sponge groups,respectively.The color difference values were 130.86±53.99 and 34.13±31.77(P<0.05),the VAS pain scores was 5.13±1.25 and 1.88±1.13(P<0.001),and the operative time was(38.17±4.56)min and(21.17±3.72)min(P<0.01),respectively,showing statistically significant differences.Conclusion Collagen sponge can be used for peri-implant keratinized gingiva augmentation.Compared with free gingival grafts,collagen sponges provide better aesthetic results,reduce operation time,and avoid the additional trauma associated with donor site harvesting.

关 键 词：种植牙 角化龈增量 胶原蛋白海绵 替代物 

分 类 号：R783.6[医药卫生—口腔医学]