全胸腔镜辅助根治手术与传统术式对食管癌患者的影响  

Effects of Total Thoracoscopic Assisted Radical Surgery and Traditional Surgery on Patients with Esophageal Cancer

作　　者：王建凯 WANG Jiankai(Department of Thoracic Surgery,Yanggu County People's Hospital,Liaocheng 252300,China)

机构地区：[1]阳谷县人民医院胸外科,山东聊城252300

出　　处：《反射疗法与康复医学》2024年第16期138-140,144,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的比较全胸腔镜辅助根治手术与传统术式对食管癌患者的影响。方法选取2021年9月—2023年9月该院收治的86例食管癌患者为研究对象,按随机数字表法将其分为对照组和观察组,各43例。对照组行传统术式治疗,观察组行全胸腔镜辅助根治术治疗。对比两组围手术期指标、应激反应、肺功能、并发症发生情况。结果观察组术中出血量为(186.95±19.72)mL,少于对照组的(275.63±23.48)mL,手术时间为(191.41±16.35)min、住院时间为(10.56±1.24)d,均短于对照组的(210.56±19.83)min、(13.21±1.89)d,并发症发生率为4.65%,低于对照组的18.60%,组间差异有统计学意义(P<0.05)。术后3 d,观察组去甲肾上腺素水平为(258.84±21.36)ng/L、皮质醇水平为(170.63±13.58)mmol/L,均低于对照组的(306.75±25.69)ng/L、(219.76±16.42)mmol/L,用力肺活量为(3.01±0.51)L、第1秒用力呼气容积为(2.39±0.48)L,均大于对照组的(2.39±0.48)L、(1.45±0.37)L,呼气流量峰值为(3.29±0.34)L/s,高于对照组的(2.53±0.30)L/s,组间差异有统计学意义(P<0.05)。结论全胸腔镜辅助根治术具有创伤小、术后恢复快等优势,能够减轻应激反应,减少对食管癌患者肺功能的损伤,且并发症较少。Objective To compare the effects of total thoracoscopic assisted radical surgery and traditional surgery on patients with esophageal cancer.Methods A total of 86 patients with esophageal cancer admitted to the hospital from September 2021 to September 2023 were selected as the study objects and divided into a control group and an observation group using a random number table method,with 43 cases in each group.The control group underwent traditional surgery,while the observation group underwent total thoracoscopic assisted radical surgery.The perioperative indicators,stress response,lung function,and occurrence of complications between two groups were compared.Results The intraoperative blood loss in the observation group was(186.95±19.72)mL,which was lower than(275.63±23.48)mL the control group,the surgical time was(191.41±16.35)min and hospital stay was(10.56±1.24)d,which were shorter than(210.56±19.83)min and(13.21±1.89)d in the control group's,the incidence of complications was 4.65%,which was lower than 18.60%control group's,the differences between the groups were statistically significant(P<0.05).Three days after surgery,the levels of norepinephrine and cortisol in the observation group were(258.84±21.36)ng/L and(170.63±13.58)mmol/L,both lower than(306.75±25.69)ng/L and(219.76±16.42)mmol/L in the control group's,forced lung capacity was(3.01±0.51)L,forced expiratory volume at the first second was(2.39±0.48)L,all greater than(2.39±0.48)L,(1.45±0.37)L in the control group,the peak expiratory flow was(3.29±0.34)L/s,which was higher than(2.53±0.30)L/s in the control group,the differences between groups were statistically significant(P<0.05).Conclusion Thoracoscopic assisted radical surgery has advantages such as minimal trauma and fast postoperative recovery,which can reduce stress reactions,minimize lung function damage to esophageal cancer patients,and have fewer complications.

关 键 词：食管癌 应激反应 肺功能 并发症 

分 类 号：R735.1[医药卫生—肿瘤]