A new perspective on changes in vascular function due to hypoxia  

作　　者：Mengyuan Guo Weilin Liu Zirui Xu Weihao Li Jia Liu Xunming Ji 

机构地区：[1]Beijing Institute of Brain Disorders,Laboratory of Brain Disorders,Ministry of Science and Technology,Collaborative Innovation Center for Brain Disorders,Beijing Advanced Innovation Center for Big Data-based Precision Medicine,Capital Medical University,Beijing 100069,China [2]Department of Neurosurgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China

出　　处：《Journal of Translational Neuroscience》2024年第3期1-14,共14页转化神经科学电子杂志（英文）

摘　　要：This review discusses the functions of blood vessels such as coagulation,regulation,immunity,endocrinology,and nerve conduction from a new perspective and suggests that hypoxia plays a common role in the changes in vascular function in various cardiovascular and cerebrovascular diseases.Therefore,it is oxygen therapy regulation may be a particularly beneficial means by which to regulate vascular function due to its low risk of harm and ease of implementation.Further,the authors have identified a link between vascular function and diseases caused by endogenous hypoxia and analyzed it in depth.The potential effects of hypoxia regulation schemes such as hyperxia,hyperoxic-hypoxia alternations,hypoxia preconditioning,and intermittent hypoxia on vascular function are also discussed,and we present theoretical support for targeted vascular therapy.

关 键 词：blood vessel function HYPOXIA hypoxia regulation vascular disease vascular intervention 

分 类 号：R543[医药卫生—心血管疾病]