血塞泰联合针刺、头部刮痧对脑梗死恢复期患者脑CT血流灌注成像指标、血液流变学和血小板-白细胞聚集体的影响  

Effects of Xuesaitai Combined with Acupuncture and Head Scraping on Cerebral CT Perfusion Imaging Indexes,Hemorheology and Platelet-Leukocyte Aggregates in Patients with Convalescent Cerebral Infarction

作　　者：申思[1] 任欣[1] 郭志华[2] 刘剑勇[1] 齐婧[3] SHEN Si;REN Xin;GUO Zhi-hua;LIU Jian-yong;Qi Jing(Department of Geriatrics,The First Affliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha,Hunan,410007,China;Department of Outpatient,The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha,Hunan,410007,China;Department of Neurology,The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha,Hunan,410007,China)

机构地区：[1]湖南中医药大学第一附属医院老年病科,湖南长沙410007 [2]湖南中医药大学第一附属医院门诊,湖南长沙410007 [3]湖南中医药大学第一附属医院神经内科,湖南长沙410007

出　　处：《现代生物医学进展》2024年第20期3863-3866,共4页Progress in Modern Biomedicine

基　　金：湖南省卫生健康委科研计划项目(202203074016,202203012675);湖南省自然科学基金青年项目(2021JJ40426)。

摘　　要：目的:观察血塞泰联合针刺、头部刮痧对脑梗死恢复期患者脑CT血流灌注成像指标、血液流变学和血小板-白细胞聚集体的影响。方法:将120例风痰阻络型脑梗死恢复期患者按随机数字表法分为A、B、C、D、E、F组,每组20例。对比六组治疗前后的脑CT血流灌注成像指标、血液流变学指标、血小板-白细胞聚集体指标。结果:与A组相比,B组、C组、D组、E组、F组治疗后平均通过时间(MTT)、血小板单核细胞聚集体(PMA)、全血低切黏度、血小板白细胞聚集体(PLA)、全血高切黏度、血小板中性粒细胞聚集体(PNA)、血浆黏度、血小板淋巴细胞聚集体(Ply A)更低,局部脑血流量(r CBF)、局部脑血容积(r CBV)更高(P<0.05)。D组、E组、F组治疗后各项指标优于B组、C组(P<0.05),其中F组治疗后各项指标最优(P<0.05)。结论:血塞泰联合针刺、头部刮痧治疗风痰阻络型脑梗死恢复期患者,可改善脑CT血流灌注成像指标、血小板-白细胞聚集体和血液流变学。Objective:To observe the effects of xuesaitai combined with acupuncture and head scraping on cerebral CT perfusion imaging indexes,hemorheology and platelet-leukocyte aggregates in patients with convalescent cerebral infarction.Methods:120 patients with convalescent cerebral infarction of wind-phlegm blocking collaterals type were divided into groups A,B,C,D,E and F according to the random number table method,with 20 cases in each group.The cerebral CT perfusion imaging indexes,hemorheology indexes and platelet-leukocyte aggregates were compared before and after treatment in six groups.Results:Compared with group A,the mean transit time(MTT),platelet monocyte aggregation(PMA),whole blood low shear viscosity,platelet leukocyte aggregation(PLA),whole blood high shear viscosity,platelet neutrophil aggregation(PNA),plasma viscosity,platelet lymphocyte aggregation(Ply A)were lower in group B,group C,group D,group E and group F after treatment,and local cerebral blood flow(r CBF)and local cerebral blood volume(r CBV)were higher(P<0.05).The indexes in group D,group E and group F were better than those in group B and group C(P<0.05),and the indexes in group F were the best after treatment(P<0.05).Conclusion:Xuesaitai combined with acupuncture and head scraping in the treatment of convalescent patients with wind-phlegm blocking collaterals type cerebral infarction,which can improve cerebral CT perfusion imaging indexes,platelet-leukocyte aggregates and hemorheology.

关 键 词：血塞泰 针刺 头部刮痧 脑梗死恢复期 脑CT血流灌注成像 血液流变学 血小板-白细胞聚集体 

分 类 号：R743[医药卫生—神经病学与精神病学]