乳腺癌患者生育力保存及促排卵方案的选择  

Selection of fertility preservation and ovulation promotion in breast cancer patients

作　　者：杨小玉 李延 胡方方 张翠莲 梁琳琳 Yang Xiaoyu;Li Yan;Hu Fangfang;Zhang Cuilian;Liang Linlin(Reproductive Medicine Center of Henan Provincial People's Hospital,Zhengzhou University People's Hospital,Zhengzhou 450003,China)

机构地区：[1]郑州大学人民医院河南省人民医院生殖医学中心,郑州450003

出　　处：《中华生殖与避孕杂志》2024年第10期1031-1035,共5页Chinese Journal of Reproduction and Contraception

基　　金：河南省医学科技攻关计划省部共建项目(SBGJ202001002)。

摘　　要：乳腺癌是目前全球女性发病率最高的恶性肿瘤。肿瘤在治疗过程中,放疗、化疗及内分泌治疗会产生不同程度的生殖毒性,对患者生育力造成损害。辅助生殖技术使乳腺癌患者的生育力有机会得到保存,其过程多依赖于促排卵治疗。治疗过程需要考虑时效性、安全性等问题。患者在肿瘤治愈后的妊娠时机及安全性,同样受到关注。本文就乳腺癌治疗对女性生育力的影响、乳腺癌女性生育力保存方案、促排卵方案的治疗、妊娠时机的选择及妊娠安全性方面进行综述,以期为临床应用提供参考。Breast cancer is currently the most common malignant tumor.During the treatment of tumors,radiotherapy,chemotherapy and endocrine therapy will produce different reproductive toxicity and cause damage to the patient's fertility.Assisted reproductive technology allows breast cancer patients to preserve their fertility,and fertility preservation process relies on ovulation stimulating treatment.The treatment process needs to consider issues such as timeliness and safety.The timeliness and safety of pregnancy after tumor therapy are also considered.This article reviews the effects of breast cancer treatment on female fertility,female fertility preservation regimens,ovulation induction regimens,pregnancy timing selection,and pregnancy safety,to provide reference for clinical application.

关 键 词：乳腺癌 生育力保存 促排卵方案 个体化选择 

分 类 号：R737.9[医药卫生—肿瘤]