内镜检查在结直肠癌防治中的应用及研究进展  

Progress on Application of Endoscopy in Prevention and Treatment of Colorectal Cancer

作　　者：张兴龙 蔡林 朱称心 房怡 郭兰伟 ZHANG Xinglong;CAI Lin;ZHU Chenxin;FANG Yi;GUO Lanwei(Department of Clinical Research Management,The Affiliated Cancer Hospital of Zhengzhou University&Henan Cancer Hospital,Zhengzhou 450008,China;School of Public Health,Zhengzhou University,Zhengzhou 450001,China)

机构地区：[1]郑州大学附属肿瘤医院/河南省肿瘤医院临床研究管理部,河南郑州450008 [2]郑州大学公共卫生学院,河南郑州450001

出　　处：《肿瘤学杂志》2024年第10期825-832,共8页Journal of Chinese Oncology

基　　金：河南省中青年卫生健康科技创新优秀人才培养项目(YXKC2022045)。

摘　　要：结直肠癌作为全球常见的恶性肿瘤,其发病率和死亡率均居高位。内镜筛查,尤其是结肠镜检查,被证实为结直肠癌预防和早期发现的有效手段。通过定期的内镜筛查,及时发现并切除结直肠进展期腺瘤,可显著提高患者的生存率。然而,内镜筛查在实际应用中面临诸多挑战,包括患者依从性和技术人员水平等,这些因素限制了内镜筛查的效果。全文描述了内镜筛查技术在结直肠癌预防、早期发现和治疗中的应用。阐述了结直肠癌内镜筛查技术的发展现状,包括从早期硬管式内镜到最新的胶囊内镜的演进,并探讨了各种内镜技术的优势与局限。此外,还讨论了国内外结直肠癌筛查指南及其内镜筛查推荐,以及提高筛查依从性的策略和挑战,旨在为结直肠癌的防控提供参考依据。通过持续的技术创新和筛查策略的优化,期望未来能进一步提升内镜筛查的精确性和普及率,从而在全球范围内降低结直肠癌的疾病负担。Colorectal cancer is a common malignant tumor worldwide with a high incidence and mortality rate.Endoscopic screening has been proven to be an effective tool for colorectal cancer prevention and early detection.With regular endoscopic screening,survival can be significantly improved through timely detection and removal of lesions in patients with colorectal progressive adenomas.However,the compliance of patients and skills of physicians may affect the effectiveness of endoscopic screening.This paper describes the use of endoscopic screening techniques in the prevention,early detection,and treatment of colorectal cancer;the evolution of endoscopic techniques from early rigid-tube endoscopy to the latest capsule endoscopy,and the advantages and limitations of various endoscopic techniques.In addition,this paper discusses national and international guidelines for colorectal cancer screening and their recommendations for endoscopic screening,as well as strategies and challenges to improve screening adherence.Through continuous innovation and optimization of screening strategies,it is expected that the accuracy and prevalence of endoscopic screening will be further improved in the future,thereby reducing the disease burden of colorectal cancer globally.

关 键 词：结肠肿瘤 直肠肿瘤 内镜筛查 结肠镜 预防 

分 类 号：R735.35[医药卫生—肿瘤] R735.37[医药卫生—临床医学]