某医院药品不良反应上报工作的分析  

Analysis of the adverse drug reactions reported in a hospital

作　　者：敖娇 杨胜强 杨霄 AO Jiao;YANG Sheng-qiang;YANG Xiao(Yinjiang Tujia and Miao Autonomous County Hospital of Traditional Chinese Medicine,Yinjiang 555200,China)

机构地区：[1]印江土家族苗族自治县中医医院,555200

出　　处：《中国现代药物应用》2024年第21期154-157,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析某医院药品不良反应上报工作,提升药学服务能力。方法通过国家药品不良反应监测系统对某医院2010年1月~2019年8月的中、西药制剂不良反应情况进行汇总,按剂型分类,分别从年龄、发生时间、处理措施主要累及器官、严重程度进行统计分析。结果2010年1月~2019年8月共计发生不良反应1398例,其中中药制剂发生不良反应246例(17.60%),西药制剂发生不良反应1152例(82.40%),整体呈现出逐年递增的趋势。粉针剂与注射液皆是中、西药制剂不良反应发生的主要剂型。口服中药制剂发生不良反应的主要是胶囊剂与颗粒剂;口服西药制剂发生不良反应的主要是片剂与胶囊剂。中、西药制剂发生不良反应患者的年龄集中在≥60岁,发生时间主要在0~30 min,不良反应的处理方法多为用药抢救、更换液体。结论药品不良反应上报工作是药物警戒工作内容之一,是对风险的认知以及控制,基层医疗机构应该足够重视药品不良反应上报工作,提高自身药学服务能力。Objective To analyze the reporting of adverse drug reactions(ADR)in a hospital,so as to improve the pharmaceutical service ability.Methods The adverse reactions of Chinese and Western medicine preparations in a hospital from January 2010 to August 2019 were summarized by the National Adverse Drug Reaction Monitoring System,classified by dosage form,and statistically analyzed from age,occurrence time and treatment measures,main organs involved and severity.Results A total of 1398 cases of adverse reactions occurred from January 2010 to August 2019,of which 246 cases(17.60%)occurred in Chinese medicine preparations and 1152 cases(82.40%)occurred in Western medicine preparations,with an overall increasing trend year by year.Powder injection and injection were the main dosage forms in which the adverse reactions of Chinese and Western medicine preparations occurred.The adverse reactions of Chinese medicine preparations were mainly capsules and granules,and the adverse reactions of Western medicine preparations were mainly tablets and capsules.The adverse reactions of Chinese and Western medicine preparations occurred mainly at the age of≥60 years,and occurrence the time was 0-30 min.The treatment methods were mostly drug rescue and liquid replacement.Conclusion The reporting of adverse drug reactions is one of the contents of pharmacovigilance,and it is the recognition and control of risks.Grass roots medical institutions should pay enough attention to the reporting of adverse drug reactions to improve their pharmaceutical service capabilities.

关 键 词：药品不良反应 中药制剂 西药制剂 粉针剂 注射液 

分 类 号：R95[医药卫生—药学]