Hedy:a groundbreaking revelation of cartilage oxygen homeostasis  

作　　者：Haoliang Hu Labapuchi Kerui Huang Yanling Long Linxi Chen 

机构地区：[1]College of Medicine,Hunan University of Arts and Science,Changde,China [2]Institute of Pharmacy and Pharmacology,College of Basic Medical Science,Hengyang Medical School,University of South China,Hengyang,China [3]The Second Affiliated Hospital,Department of Pain and rehabilitation,Hengyang Medical School,University of South China,Hengyang,China

出　　处：《Acta Biochimica et Biophysica Sinica》2024年第9期1410-1413,共4页生物化学与生物物理学报（英文版）

基　　金：supported by the grants from the National Natural Science Foundation of China(No.82304495);the Natural Science Foundation of Hunan Province(No.2024JJ4031 and 2022JJ40291);the Key Project of the Education Department of Hunan Province(No.23A0505);the Science and Technology Innovation Guidance Project of Changde City(No.2023ZD03);the Doctoral Initiation Project of Hunan University of Arts and Science(No.21BSQD16).

摘　　要：Oxygen plays a vital role in cellular respiration within the human body,providing essential energy for life sustenance and serving as a key component in important biochemical reactions necessary for cellular homeostasis and maintaining cellular viability.In human erythrocytes,hemoglobin(Hb)is central to the process of binding with and releasing oxygen,thereby regulating systemic oxygenation and contributing significantly to physiological homeostasis[1].While oxygen supply and adaptation mechanisms are well understood in vascularized tissues,avascular tissues present unique challenges.Recent studies have shed light on the multifaceted roles of Hb in avascular tissues.

关 键 词：HOMEOSTASIS BREAKING thereby 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]