钆塞酸二钠增强MRI影像组学在肝细胞癌诊疗中的研究进展  

Advances in radiomics based on gadoxetic acid-enhanced MRI for the diagnosis and treatment of hepatocellular carcinoma

作　　者：赵雨蒙 谢双双[2] 沈文(审校)[2] ZHAO Yumeng;XIE Shuangshaung;SHEN Wen(Nankai University,Medical school,Tianjin 300071,China;Department of Radiology,The First Central Hospital of Tianjin,Tianjin Institute of Imaging Medicine)

机构地区：[1]南开大学医学院,天津300071 [2]天津市第一中心医院放射科,天津市影像医学研究所

出　　处：《国际医学放射学杂志》2024年第6期675-682,共8页International Journal of Medical Radiology

基　　金：国家自然科学基金(82271971);天津市科委自然科学基金(21JCYBJC01640);天津市医学重点学科(专科)建设项目(TJYXZDXK-041A)。

摘　　要：钆塞酸二钠(Gd-EOB-DTPA)增强MRI能提供具有肝细胞特异性的肝胆期影像,增加了对肝细胞癌诊断的敏感度。影像组学通过高通量提取肿瘤微观定量特征,在肝细胞癌的诊疗各方面呈现良好的应用前景。就基于Gd-EOB-DTPA增强MRI的影像组学研究在肝细胞癌诊断、肿瘤增殖、侵袭性等生物学行为及肿瘤预后预测中的应用及其进展进行综述。Gadoxetic acid disodium(Gd-EOB-DTPA)-enhanced MRI provides hepatocyte-specific hepatobiliary phase imaging,increasing the sensitivity in diagnosing hepatocellular carcinoma(HCC).Radiomics,by extracting high-throughput quantitative tumor micro-features,shows promising applications across various aspects of HCC diagnosis and treatment.This review summarizes the applications and recent advances of Gd-EOB-DTPA-enhanced MRI-based radiomics in diagnosing HCC,assessing tumor proliferation,invasiveness,and other biological behaviors,as well as predicting prognosis.

关 键 词：影像组学 钆塞酸二钠 磁共振成像 肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]