MRI无创评估肝纤维化的研究进展  

Research progress on magnetic resonance imaging for non-invasive evaluation of liver fibrosis

作　　者：朱珍 梁宗辉(审校) ZHU Zhen;LIANG Zonghui(Department of Radiology,Putuo People’s Hospital,Tongji University,Shanghai 200060,China;Department of Radiology,Jing’an District Centre Hospital(Fudan University Huashan Hospital Jing’an Branch),Fudan University)

机构地区：[1]同济大学附属普陀人民医院放射科,上海200060 [2]上海市静安区中心医院(复旦大学附属华山医院静安分院)放射科

出　　处：《国际医学放射学杂志》2024年第6期683-689,共7页International Journal of Medical Radiology

基　　金：上海市科技创新行动计划医学创新研究专项项目(21Y11910600);上海市静安区卫生健康委员会医学学科系列项目建设计划项目(2021PY01)。

摘　　要：肝纤维化为细胞外基质成分在肝脏中过量沉积,可导致肝脏结构和功能受损。诊断肝纤维化的金标准是有创的肝活检。MRI作为一种无创性技术在评估肝纤维化中发挥重要作用。MR弹性成像(MRE)、扩散加权成像(DWI)和基于扩散的高级模型、钆塞酸二钠(Gd-EOB-DTPA)增强成像、定量T1技术、定量磁化率成像(QSM)等MRI技术和基于MRI的人工智能等不断应用于无创评估肝纤维化。就多种MRI技术和基于MRI的人工智能对肝纤维化无创评估的研究进展进行综述。Liver fibrosis is characterized by the excess deposition of extracellular matrix components within the liver,which can impair its structure and function.The gold standard for diagnosing liver fibrosis is an invasive liver biopsy.As a non-invasive technique,MRI plays an important role in evaluation of liver fibrosis.MRI techniques such as magnetic resonance elastography,diffusion weighted imaging and advanced diffusion models,Gd-EOB-DTPA-enhanced MRI,quantitative T1 technology,quantitative susceptibility mapping,and MRI-based artificial intelligence are increasingly applied in this field.We reviewed recent research advancements in various MRI techniques and MRI-based artificial intelligence for the non-invasive evaluation of liver fibrosis.

关 键 词：肝纤维化 磁共振成像 磁共振弹性成像 扩散加权成像 人工智能 

分 类 号：R575[医药卫生—消化系统] R445.2[医药卫生—内科学]