计算机化认知矫正治疗对慢性精神分裂症患者认知功能和生命质量影响  

Effects of computerized cognitive correction therapy on cognitive function and quality of life in patients with chronic schizophrenia

作　　者：胡建军[1] 孔燕 孙喜蓉[1] 闵海瑛[1] 张洁[1] 朱晓春 杨振东[1] 倪爽旻 HU Jianjun;KONG Yan;SUN Xirong(Shanghai Pudong New Area Mental Health Center Tongji University Affiliated Mental Health Center,Tongji University Clinical Research Center for Mental Disorders,Shanghai 200124,China)

机构地区：[1]上海市浦东新区精神卫生中心/同济大学附属精神卫生中心/同济大学精神疾病临床研究中心,上海200124

出　　处：《国际精神病学杂志》2024年第5期1397-1400,1404,共5页Journal Of International Psychiatry

基　　金：上海市浦东新区科技发展民生科研专项项目(PKJ2023-Y80);上海市浦东新区国家中医药发展综合改革建设项目(PDZY-2022-05-01)。

摘　　要：目的 观察计算机化认知矫正治疗对慢性精神分裂症患者的影响。方法 选择医院治疗的120例慢性精神分裂症患者,2017年4月~2020年6月病例入组,分组方式为随机数字表法。基础组60例,给予患者常规药物治疗,计算机化认知矫正组60例,基础组治疗基础上同时进行计算机化认知矫正治疗,治疗前、后进行阳性和阴性症状量表(PANSS)、威斯康星卡片分类测试(WCST)、蒙特利尔认知评估量表(MoCA)、社会功能缺陷筛选量表(SDSS)、世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评价。结果 计算机化认知矫正组PANSS评分、SDSS评分、总错误数较基础组低(P<0.05),计算机化认知矫正组完成分类数、总应答数、正确数、MoCA、WHOQOL-BREF评分较基础治疗组高(P<0.05)。结论 计算机化认知矫正治疗慢性精神分裂症患者,可改善患者精神状态,提升认知功能、社会功能及生命质量。Objective To observe the effect of computerized cognitive correction therapy on patients with chronic schizophrenia.Methods A total of 120 patients with chronic schizophrenia treated in the hospital were selected and enrolled from April 2017 to June 2020,so the patients were grouped by random number table method.The basic group of 60 patients received conventional Western medicine treatment,and the computerized cognitive correction group of 60 patients received computerized cognitive correction treatment at the same time.Positive and Negative Symptom Scale(PANSS),Wisconsin Card Classification Test(WCST),Montreal Cognitive Assessment Scale(MoCA),Social Disability Screening Scale(SDSS),and World Health Organization Quality of Life(WHOQOL-BREF)were evaluated before and after treatment.Results PANSS scores,SDSS scores and total errors in the computerized cognitive correction group were lower than those in the basic treatment group(P<0.05),while the number of completed categories,total responses,correct numbers,MoCA scores and WHOQOL-BREF scores in the computerized cognitive correction group were higher than those in the basic treatment group(P<0.05).Conclusion Computerized cognitive correction can improve mental state,cognitive function,social function and life quality of patients with chronic schizophrenia.

关 键 词：计算机化认知矫正治疗 慢性精神分裂症 认知功能 社会功能 生命质量 

分 类 号：R749.05[医药卫生—神经病学与精神病学]