老年帕金森病患者抑郁现状及与认知功能的关系  

Depression status in elderly Parkinson's disease patients and its correlation with cognitive function

作　　者：李振科 魏毛妮 姬松波[1] LI Zhenke;WEI Maoni;JI Songbo(Jiaozuo Second People's Hospital Henan,Jiaozuo 454000,China)

机构地区：[1]焦作市第二人民医院,焦作454000

出　　处：《国际精神病学杂志》2024年第5期1500-1503,共4页Journal Of International Psychiatry

基　　金：焦作市科技计划项目(编号:2023230035)。

摘　　要：目的 探讨老年帕金森病患者抑郁现状及其与认知功能的相关性。方法 选取本院2021年3月~2024年3月期间收治的80例老年帕金森病患者为研究对象。分别采用抑郁自评量表(Self Rating Depression Scale,SDS)、简易智能精神状态检查量表(Mini Mental State Examination,MMSE)评估患者抑郁状态及认知功能,观察不同基础资料患者的抑郁状态,多元线性回归分析抑郁状态的相关影响因素及其与认知功能的相关性。结果 80例患者的SDS为(61.25±13.26)分。不同性别、年龄的SDS评分比较,差异均无统计学意义(P>0.05);不同病程、受教育程度、月收入、MMSE的SDS评分比较,差异有统计学意义(P<0.05)。以SDS评分为因变量,以病程、受教育程度、月收入、MMSE为自变量进行多元线性回归分析,结果显示,SDS评分与病程呈正相关,SDS与受教育程度、月收入、MMSE呈负相关,差异均有统计学意义(P<0.05)。结论 老年帕金森病患者多伴随抑郁情绪,且抑郁情绪与病程呈正相关,与受教育程度、月收入、MMSE分值呈负相关,即患者病程越长,患者抑郁情况越严重,受教育程度、月收入、MMSE分值越高,患者抑郁程度越轻。Objective To explore the current status of depression in elderly Parkinson's disease patients and its correlation with cognitive function.Methods 80 elderly Parkinson's disease patients admitted to our hospital from March 2021 to March 2024 were selected as the study subjects.The depression status and cognitive function of patients were evaluated using the Self Rating Depression Scale(SDS)and the Mini Mental State Examination(MMSE),respectively.The depression status of patients with different baseline data was observed,and multiple linear regression analysis was conducted to identify the relevant influencing factors of depression and their correlation with cognitive function.Results The SDS of 80 patients was(61.25±13.26)points.There was no statistically significant difference in SDS between different genders and ages(P>0.05).The SDS comparison of different disease courses,education levels,monthly income,and MMSE showed statistically significant differences(P<0.05).Multiple linear regression analysis was conducted with SDS as the dependent variable and disease course,education level,monthly income,and MMSE as independent variables.The results showed that SDS was positively correlated with disease course,while SDS was negatively correlated with education level,monthly income,and MMSE,with statistical significance(P<0.05).Conclusion Elderly Parkinson's disease patients are often accompanied by depressive emotions,which are positively correlated with the course of the disease and negatively correlated with education level,monthly income,and MMSE score.That is,the longer the course of the disease,the more severe the depression situation of the patient.The higher the education level,monthly income,and MMSE score,the milder the depression level of the patient.

关 键 词：老年帕金森病 抑郁现状 认知功能 相关性 

分 类 号：R749.1[医药卫生—神经病学与精神病学]