缺血性脑卒中合并抑郁患者的MRI特征  

The features of MRI in ischemic stroke patients with depression

作　　者：陈彦君 王同明[1] 易慧洋 杨达 CHEN Yanjun;WANG Tongming;YI Huiyang(Henan Provincial Hospital of Traditional Chinese Medicine(Second Affiliated Hospital of Henan University of Traditional Chinese Medicine),Zhengzhou 450000,China)

机构地区：[1]河南省中医院/河南省中医药大学第二附属医院,郑州450000

出　　处：《国际精神病学杂志》2024年第5期1530-1532,共3页Journal Of International Psychiatry

基　　金：河南省中医药科学研究专项课题(编号:20-21ZY2112)。

摘　　要：目的 分析缺血性脑卒中(IS)合并抑郁患者的MRI特征。方法 以2019年8月~2022年12月本院94例IS患者作为研究对象,将抑郁自评量表(SDS)≥53分的46例作为研究组,SDS<53分的48例作为对照组。比较两组的MRI特征。结果 研究组的额叶、颞叶、基底节区的缺血比例均显著高于对照组,差异均有统计学意义(P<0.05);两组顶叶、枕叶、丘脑、内囊、海马体的缺血比例比较,差异均无统计学意义(P>0.05)。研究组额叶、颞叶、基底节区的表观扩散系数(ADC)值均高于对照组,差异均有统计学意义(P<0.05)。结论 IS合并抑郁患者的额叶、颞叶、基底节区的缺血比例显著较高,临床可根据MRI相关参数,防治本病。Objective To analyze MRI features in patients with ischemic stroke(IS)combined with depression.Methods Ninety-four cases of IS patients in our hospital from August 2019 to December 2022 were used as the study population.Forty-six cases with depression self-rating scale(SDS)≥ 53 were used as the study group,and 48 cases with SDS < 53 were used as the control group.MRI characteristics of the two groups were compared.Results The proportion of ischemia in the frontal,temporal,and basal ganglia regions was significantly higher in the study group than in the control group(P<0.05).There were not statistically differences of ischemia in the parietal,occipital,thalamus,internal capsule,and hippocampus between two groups(P>0.05).The apparent diffusion coefficient(ADC)values in the frontal,temporal,and basal ganglia regions were higher in the study group than those in the control group(P<0.05).Conclusion IS patients combined with depression have a significantly higher proportion of ischemias in the frontal,temporal,and basal ganglia regions,and the disease maybe can be prevented and treated clinically based on MRI-related parameters.

关 键 词：IS 抑郁 MRI ADC值 

分 类 号：R749.2[医药卫生—神经病学与精神病学]