常规超声联合超声造影观察无功能性胰腺神经内分泌肿瘤病理分级的影响因素  

Conventional ultrasound combined with contrast-enhanced ultrasound for analyzing impact factors of pathological grade of nonfunctional pancreatic neuroendocrine tumor

作　　者：霍婷婷[1] 靳慧芳[2] 王红鹄 王帅[1] HUO Tingting;JIN Huifang;WANG Honghu;WANG Shuai(Department of Ultrasound,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Blood Transfusion,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院超声科,河南郑州450052 [2]郑州大学第一附属医院输血科,河南郑州450052

出　　处：《中国介入影像与治疗学》2024年第11期670-674,共5页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的基于常规超声联合超声造影观察无功能性胰腺神经内分泌肿瘤(PNET)病理分级的影响因素。方法回顾性纳入86例单发无功能性PNET,根据病理结果将其分为G1级组(n=48)、G2级组(n=25)及G3级组(n=13);比较组间临床及超声资料,并以logistic回归分析筛选影响无功能性PNET病理分级的因素。结果3组病灶形态、边界、有无周围脏器/血管受侵,以及病灶动脉期强化程度、静脉期强化程度及总强化模式差异均有统计学意义(P均<0.05);其中,病灶形态、边界、动脉期及静脉期强化程度为无功能性PNET病理分级的独立影响因素(P均<0.05)。结论病灶形态、边界、动脉期及静脉期强化程度均为无功能性PNET病理分级的影响因素。Objective To explore the impact factors of pathological grade of nonfunctional pancreatic neuroendocrine tumor(PNET)based on conventional ultrasound and contrast-enhanced ultrasound(CEUS).Methods Totally 86 patients with single lesion of nonfunctional PNET were retrospectively enrolled and divided into G1 grade group(n=48),G2 grade group(n=25)and G3 grade group(n=13)based on pathological results.Clinical and ultrasonic data were compared among groups,and logistic regression analysis was used to screen impact factors of pathological grade of nonfunctional PNET.Results Significant differences of the morphology,boundary,surrounding organs/blood vessels invasion or not,degree of arterial phase enhancement,venous phase enhancement and total enhancement pattern of lesions were found among 3 groups(all P<0.05).The morphology,boundary,degree of arterial phase enhancement and degree of venous phase enhancement of lesions were all independent impact factors of pathological grade of nonfunctional PNET(all P<0.05).Conclusion Morphology,boundary,degree of arterial phase enhancement and venous phase enhancement of lesions were all impact factors of pathological grade of nonfunctional PNET.

关 键 词：胰腺肿瘤 神经内分泌瘤 超声检查 

分 类 号：R735.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]