超声引导下核芯针穿刺活检在口腔颌面部肿瘤中的应用及诊断效能评价  

The clinical application and diagnostic performance of ultrasound-guided core needle biopsy in the diagnosis of oral and maxillofacial tumors

作　　者：周晓凯 徐志铭 徐凤 李志萍 孟箭 ZHOU Xiaokai;XU Zhiming;XU Feng;LI Zhiping;MENG Jian(Xuzhou Clinical College of Xuzhou Medical University,221004,China)

机构地区：[1]徐州医科大学徐州临床学院,221004 [2]徐州市中心医院口腔科

出　　处：《实用口腔医学杂志》2024年第6期834-839,共6页Journal of Practical Stomatology

基　　金：国家口腔疾病临床医学研究中心开放课题(编号:NCRCO-202101);徐州市科技计划项目(编号:KC21187)。

摘　　要：目的:评估超声引导下核芯针穿刺活检(US-CNB)在口腔颌面部肿瘤中的应用及诊断效能。方法:回顾性分析US-CNB患者192例的临床资料和病理诊断结果,探讨US-CNB对口腔颌面部肿瘤诊断效能。结果:在192例病例中,恶性肿瘤87例,良性肿瘤及病变105例,US-CNB诊断灵敏度为93.1%、特异度100%、阳性预测值100%、阴性预测值94.6%、准确率96.9%、误诊率3.1%。Kappa值为0.937(95%CI:0.887-0.986)。US-CNB对口腔颌面部肿瘤的ROC曲线下面积AUC值=0.966(95%CI:0.929-0.986)。结论:US-CNB对口腔颌面部肿瘤具有较高的诊断价值,可成为评估口腔颌面部肿瘤的标准程序。Objective:To evaluate the efficacy of ultrasound-guided core needle biopsy(US-CNB)in the diagnosis of oral and maxillofacial tumors.Methods:The clinical records,radiology and histopathology reports along with the biopsy of 192 patients with oral and maxillofacial tumors who received US-CNB were retrospectively reviewed and stastactivelly analyized.Results:The overall sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV)and accuracy of US-CNB for the diagnosis of oral and maxillofacial tumors were 93.1%,100%,100%,94.6%and 96.9%,respectively.The misdiagnosis ratio was 3.1%.Kappa value was 0.937(95%CI:0.887~0.986).The AUC of ROC for the diagnosis was 0.966(95%CI:0.929~0.986).Conclusion:US-CNB is an accurate and efficient method for the histological diagnosis of oral and maxillofacial tumors,and can be considered as the first-line diagnostic modality.

关 键 词：口腔颌面部肿瘤 超声检查 核芯针穿刺活检 诊断 活检技术 

分 类 号：R739.8[医药卫生—肿瘤]