肝细胞癌以手术为基础的综合治疗——《原发性肝癌诊疗指南(2024版)》解读  

Surgery-based comprehensive treatment for hepatocellular carcinoma-interpretation of"Guidelines for Diagnosis and Treatment of Primary Liver Cancer(2024 Edition)"

作　　者：文天夫[1] 李川[1] 张晓赟[1] 彭伟[1] 沈俊颐 WEN Tian-fu;LI Chuan;ZHANG Xiao-yun;PENG Wei;SHEN Jun-yi(Division of Liver Surgery,Department of General Surgery,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院普通外科肝脏外科病房,四川成都610041

出　　处：《实用医院临床杂志》2024年第6期11-15,共5页Practical Journal of Clinical Medicine

基　　金：国家重点研发项目“优化消化肿瘤HFRT治疗方案”(编号:2022YFC2503701)。

摘　　要：针对肝细胞癌初诊时64%为中晚期、切除后5年复发率高达70%的两大突出问题,《原发性肝癌诊疗指南》提出了以手术治疗为基础的肝细胞癌综合治疗策略。本文就其重要内容包括肝切除术与肝移植术治疗肝癌、肝癌的辅助治疗、肝癌的新辅助治疗和肝癌的转化治疗与转化切除四方面进行了解读。There are two major problems in diagnosis and treatment of hepatocellular carcinoma(HCC):64%of HCC is in the intermediate and advanced stages when first diagnosed,and the recurrence rate is as high as 70%after 5 years of resection.The"Guidelines for the Diagnosis and Treatment of Primary Liver Cancer"proposes a comprehensive treatment strategy for HCC based on surgical treatment.This paper will elaborate the main contents including HCC resection,adjuvant,neoadjuvant and conversion therapy for HCC of the strategy.

关 键 词：肝细胞癌 手术切除 辅助治疗 新辅助治疗 转化治疗 

分 类 号：R735.7[医药卫生—肿瘤]