脐针联合帕罗西汀治疗肝郁脾虚型抑郁症临床研究  

Clinical Study on Navel Acupuncture Combined with Paroxetine for Depression of Liver Constraint and Spleen Deficiency Type

作　　者：郑蔚 叶子甸 叶鑫武 应孝全 蔡子耀 戴萌萌 周容容 ZHENG Wei;YE Zidian;YE Xinwu;YING Xiaoquan;CAI Ziyao;DAI Mengmeng;ZHOU Rongrong(Department of Psychiatric Rehabilitation,The Seventh People's Hospital of Wenzhou,Wenzhou Zhejiang 325000,China)

机构地区：[1]温州市第七人民医院精神康复科,浙江温州325000

出　　处：《新中医》2024年第22期120-123,共4页New Chinese Medicine

基　　金：温州市科技局项目(Y20220232)。

摘　　要：目的:观察脐针联合帕罗西汀治疗肝郁脾虚型抑郁症的临床疗效。方法:采用随机数字表法将76例肝郁脾虚型抑郁症患者分为对照组、治疗组各38例。对照组给予帕罗西汀治疗,治疗组给予帕罗西汀联合脐针治疗,2组均治疗6周。比较2组治疗前后汉密尔顿抑郁量表-17评分(HAMD-17)、抑郁自评量表评分(SDS)、匹兹堡睡眠质量指数(PSQI)评分及中医证候积分,并评估2组临床疗效及不良反应发生情况。结果:治疗后,治疗组总有效率94.29%,高于对照组71.43%(P<0.05)。2组HAMD-17评分、SDS评分、中医证候积分、PSQI评分均低于治疗前(P<0.05),且治疗组HAMD-17评分、SDS评分、PSQI评分、中医证候积分均低于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:脐针联合帕罗西汀治疗肝郁脾虚型抑郁症,能够有效缓解患者抑郁症状,改善睡眠质量,提高临床疗效,安全性较高。Objective:To observe the clinical efficacy of navel acupuncture combined with Paroxetine on depression of liver constraint and spleen deficiency type.Methods:A total of 76 cases of patients with depression of liver constraint and spleen deficiency type were divided into the control group and the treatment group according to the random number table method with 38 cases.The control group was treated with Paroxetine,and the treatment group was treated with Paroxetine combined with navel acupuncture.Both groups were treated for six weeks.The scores of the Hamilton Depression Scale-17 score(HAMD-17),Self-Rating Depression Scale(SDS),and Pittsburgh Sleep Quality Index(PSQI),as well as traditional Chinese medicine(TCM)syndrome scores were compared between the two groups before and after treatment.The clinical efficacy and incidence of adverse reactions in the two groups were evaluated.Results:After treatment,the total effective rate of the treatment group was 94.29%,which was higher than that of 71.43%in the control group(P<0.05).The scores of HAMD-17,SDS,and PSQI,as well as TCM syndrome scores in the two groups were lower than those before treatment(P<0.05),and the scores of HAMD-17,SDS,and PSQI,as well as TCM syndrome scores in the treatment group were lower(P<0.05).There was no significant difference being found in the comparison of the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of navel acupuncture and Paroxetine in the treatment of depression of liver constraint and spleen deficiency type can effectively alleviate patients'depressive symptoms,improve sleep quality,enhance clinical efficacy,and have high safety.

关 键 词：抑郁症 肝郁脾虚证 脐针 帕罗西汀 汉密尔顿抑郁量表-17评分 抑郁自评量表评分 匹兹堡睡眠质量指数 

分 类 号：R749.4[医药卫生—神经病学与精神病学]